Treatments of choice for bullous pemphigoid.
Bullous pemphigoid (BP) is the most frequently occurring autoimmune blistering disease in Europe and North America. Although it is primarily a disease of the elderly, children and young adults can also develop it. The aim of treatment is to suppress the clinical signs and symptoms of BP without over...
Main Authors: | , |
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Format: | Journal article |
Language: | English |
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2002
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author | Cooper, S Wojnarowska, F |
author_facet | Cooper, S Wojnarowska, F |
author_sort | Cooper, S |
collection | OXFORD |
description | Bullous pemphigoid (BP) is the most frequently occurring autoimmune blistering disease in Europe and North America. Although it is primarily a disease of the elderly, children and young adults can also develop it. The aim of treatment is to suppress the clinical signs and symptoms of BP without over-treating the patient, because BP tends to spontaneously remit in most patients within approximately 5 years. Mild or localized disease may respond to super-potent topical corticosteroids alone or in combination with tetracyclines with or without niacinamide. More severe or generalized disease usually requires systemic treatment with prednisolone (dose range from 20-70 mg/d). Additional immunosuppressant therapy is necessary for more refractory disease. |
first_indexed | 2024-03-07T03:29:13Z |
format | Journal article |
id | oxford-uuid:ba1bfded-e0cc-4606-81a8-6a31b5f3d40e |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-07T03:29:13Z |
publishDate | 2002 |
record_format | dspace |
spelling | oxford-uuid:ba1bfded-e0cc-4606-81a8-6a31b5f3d40e2022-03-27T05:07:42ZTreatments of choice for bullous pemphigoid.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:ba1bfded-e0cc-4606-81a8-6a31b5f3d40eEnglishSymplectic Elements at Oxford2002Cooper, SWojnarowska, FBullous pemphigoid (BP) is the most frequently occurring autoimmune blistering disease in Europe and North America. Although it is primarily a disease of the elderly, children and young adults can also develop it. The aim of treatment is to suppress the clinical signs and symptoms of BP without over-treating the patient, because BP tends to spontaneously remit in most patients within approximately 5 years. Mild or localized disease may respond to super-potent topical corticosteroids alone or in combination with tetracyclines with or without niacinamide. More severe or generalized disease usually requires systemic treatment with prednisolone (dose range from 20-70 mg/d). Additional immunosuppressant therapy is necessary for more refractory disease. |
spellingShingle | Cooper, S Wojnarowska, F Treatments of choice for bullous pemphigoid. |
title | Treatments of choice for bullous pemphigoid. |
title_full | Treatments of choice for bullous pemphigoid. |
title_fullStr | Treatments of choice for bullous pemphigoid. |
title_full_unstemmed | Treatments of choice for bullous pemphigoid. |
title_short | Treatments of choice for bullous pemphigoid. |
title_sort | treatments of choice for bullous pemphigoid |
work_keys_str_mv | AT coopers treatmentsofchoiceforbullouspemphigoid AT wojnarowskaf treatmentsofchoiceforbullouspemphigoid |