111In-DTPA-Octreotide SPECT (OctreoScan) uptake in metastatic renal cell carcinoma to the pancreas

We report a case of late presentation of metastatic renal cell carcinoma (RCC) demonstrating intense 111In-DTPA-octreotide uptake in pancreas without recurrence at the primary site. Immunohistochemistry study revealed somatostatin receptor subtype 2 of metastatic RCC preferentially expressed on tumo...

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Main Authors: Chan, K, Luong, T, Navalkissoor, S
Format: Journal article
Language:English
Published: Lippincott, Williams & Wilkins 2018
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author Chan, K
Luong, T
Navalkissoor, S
author_facet Chan, K
Luong, T
Navalkissoor, S
author_sort Chan, K
collection OXFORD
description We report a case of late presentation of metastatic renal cell carcinoma (RCC) demonstrating intense 111In-DTPA-octreotide uptake in pancreas without recurrence at the primary site. Immunohistochemistry study revealed somatostatin receptor subtype 2 of metastatic RCC preferentially expressed on tumor endothelial cells. The typical hypervascular features of RCC with intense homogeneous contrast enhancement in the arterial phase on CT should raise the possibility of metastatic RCC. This case illustrates that RCC can demonstrate high octreotide uptake in abdominal metastases.
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spelling oxford-uuid:ba26d751-5860-47dd-9bb0-300830782d4f2022-03-27T05:07:57Z111In-DTPA-Octreotide SPECT (OctreoScan) uptake in metastatic renal cell carcinoma to the pancreasJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:ba26d751-5860-47dd-9bb0-300830782d4fEnglishSymplectic Elements at OxfordLippincott, Williams & Wilkins2018Chan, KLuong, TNavalkissoor, SWe report a case of late presentation of metastatic renal cell carcinoma (RCC) demonstrating intense 111In-DTPA-octreotide uptake in pancreas without recurrence at the primary site. Immunohistochemistry study revealed somatostatin receptor subtype 2 of metastatic RCC preferentially expressed on tumor endothelial cells. The typical hypervascular features of RCC with intense homogeneous contrast enhancement in the arterial phase on CT should raise the possibility of metastatic RCC. This case illustrates that RCC can demonstrate high octreotide uptake in abdominal metastases.
spellingShingle Chan, K
Luong, T
Navalkissoor, S
111In-DTPA-Octreotide SPECT (OctreoScan) uptake in metastatic renal cell carcinoma to the pancreas
title 111In-DTPA-Octreotide SPECT (OctreoScan) uptake in metastatic renal cell carcinoma to the pancreas
title_full 111In-DTPA-Octreotide SPECT (OctreoScan) uptake in metastatic renal cell carcinoma to the pancreas
title_fullStr 111In-DTPA-Octreotide SPECT (OctreoScan) uptake in metastatic renal cell carcinoma to the pancreas
title_full_unstemmed 111In-DTPA-Octreotide SPECT (OctreoScan) uptake in metastatic renal cell carcinoma to the pancreas
title_short 111In-DTPA-Octreotide SPECT (OctreoScan) uptake in metastatic renal cell carcinoma to the pancreas
title_sort 111in dtpa octreotide spect octreoscan uptake in metastatic renal cell carcinoma to the pancreas
work_keys_str_mv AT chank 111indtpaoctreotidespectoctreoscanuptakeinmetastaticrenalcellcarcinomatothepancreas
AT luongt 111indtpaoctreotidespectoctreoscanuptakeinmetastaticrenalcellcarcinomatothepancreas
AT navalkissoors 111indtpaoctreotidespectoctreoscanuptakeinmetastaticrenalcellcarcinomatothepancreas