Validation of a chloroquine-induced cell death mechanism for clinical use against malaria.

Validation of a chloroquine-induced cell death mechanism for clinical use against malaria.

An alternative antimalarial pathway of an 'outdated' drug, chloroquine (CQ), may facilitate its return to the shrinking list of effective antimalarials. Conventionally, CQ is believed to interfere with hemozoin formation at nanomolar concentrations, but resistant parasites are able to effl...

Bibliografiset tiedot
Päätekijät:	Ch'ng, J, Lee, Y, Gun, S, Chia, W, Chang, Z, Wong, L, Batty, K, Russell, B, Nosten, F, Renia, L, Tan, K
Aineistotyyppi:	Journal article
Kieli:	English
Julkaistu:	Nature Publishing Group 2014
Aiheet:	Malaria Pharmacology

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