Recurrent SETBP1 mutations in atypical chronic myeloid leukemia.

Recurrent SETBP1 mutations in atypical chronic myeloid leukemia.

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Atypical chronic myeloid leukemia (aCML) shares clinical and laboratory features with CML, but it lacks the BCR-ABL1 fusion. We performed exome sequencing of eight aCMLs and identified somatic alterations of SETBP1 (encoding a p.Gly870Ser alteration) in two cases. Targeted resequencing of 70 aCMLs,...

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Bibliographic Details
Main Authors: Piazza, R, Valletta, S, Winkelmann, N, Redaelli, S, Spinelli, R, Pirola, A, Antolini, L, Mologni, L, Donadoni, C, Papaemmanuil, E, Schnittger, S, Kim, D, Boultwood, J, Rossi, F, Gaipa, G, De Martini, G, di Celle, P, Jang, H, Fantin, V, Bignell, G, Magistroni, V, Haferlach, T, Pogliani, E, Campbell, P, Chase, A
Format: Journal article
Language:English
Published: 2013

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