Alpha4 integrin binding interfaces on VCAM-1 and MAdCAM-1. Integrin binding footprints identify accessory binding sites that play a role in integrin specificity.

Integrins are a family of heterodimeric adhesion receptors that mediate cellular interactions with a range of matrix components and cell surface proteins. Vascular cell adhesion molecule-1 (VCAM-1) is an endothelial cell ligand for two leukocyte integrins (alpha4beta1 and alpha4beta7). A related CAM...

全面介绍

书目详细资料
Main Authors: Newham, P, Craig, SE, Seddon, G, Schofield, N, Rees, A, Edwards, R, Jones, E, Humphries, M
格式: Journal article
语言:English
出版: 1997