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A Magnetic Resonance Imaging Contrast Agent Targeted Towards Activated Platelets Allows In Vivo Detection of Thrombosis and Monitoring of Thrombolysis
Détails bibliographiques
Auteurs principaux:
von Zur Muehlen, C
,
Elverfeldt, D
,
Moeller, J
,
Choudhury, R
,
Hagemeyer, C
,
Schwarz, M
,
Bode, C
,
Peter, K
Format:
Conference item
Publié:
2008
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Magnetic resonance imaging contrast agent targeted toward activated platelets allows in vivo detection of thrombosis and monitoring of thrombolysis.
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A single-chain antibody directed against activated platelets allows targeted magnetic resonance imaging of human thrombi at clinically relevant field strengths
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Functionalized magnetic resonance contrast agent selectively binds to glycoprotein IIb/IIIa on activated human platelets under flow conditions and is detectable at clinically relevant field strengths.
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