A Magnetic Resonance Imaging Contrast Agent Targeted Towards Activated Platelets Allows In Vivo Detection of Thrombosis and Monitoring of Thrombolysis

Geahča maid

• Magnetic resonance imaging contrast agent targeted toward activated platelets allows in vivo detection of thrombosis and monitoring of thrombolysis.
  Dahkki: von zur Muhlen, C, et al.
  Almmustuhtton: (2008)
• A single-chain antibody directed against activated platelets allows targeted magnetic resonance imaging of human thrombi at clinically relevant field strengths
  Dahkki: von zur Muhlen, C, et al.
  Almmustuhtton: (2005)
• Functionalized magnetic resonance contrast agent selectively binds to glycoprotein IIb/IIIa on activated human platelets under flow conditions and is detectable at clinically relevant field strengths.
  Dahkki: von Zur Muhlen, C, et al.
  Almmustuhtton: (2008)
• Functionalized Magnetic Resonance Contrast Agent Selectively Binds to Glycoprotein IIb/IIIa on Activated Human Platelets under Flow Conditions and Is Detectable at Clinically Relevant Field Strengths
  Dahkki: Constantin von zur Mühlen, et al.
  Almmustuhtton: (2008-03-01)
• Activated platelets canLiblilla be imaged by activation-specific glycoprotein IIb/IIIa antibodies conjugated to iron oxide microparticles in an ex vivo magnetic resonance imaging mouse model
  Dahkki: von zur Muehlen, C, et al.
  Almmustuhtton: (2007)