The roles of specific glycosylases in determining the mutagenic consequences of clustered DNA base damage.

The roles of specific glycosylases in determining the mutagenic consequences of clustered DNA base damage.

The potential for genetic change arising from specific single types of DNA lesion has been thoroughly explored, but much less is known about the mutagenic effects of DNA lesions present in clustered damage sites. Localized clustering of damage is a hallmark of certain DNA-damaging agents, particular...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Shikazono, N, Pearson, C, O'Neill, P, Thacker, J
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2006

Eitemau Tebyg

Enhanced mutagenic potential of 8-oxo-7,8-dihydroguanine when present within a clustered DNA damage site.
gan: Pearson, C, et al.
Cyhoeddwyd: (2004)

Processing of thymine glycol in a clustered DNA damage site: mutagenic or cytotoxic.
gan: Bellon, S, et al.
Cyhoeddwyd: (2009)

Biological consequences of potential repair intermediates of clustered base damage site in Escherichia coli.
gan: Shikazono, N, et al.
Cyhoeddwyd: (2009)

Corrigendum to "Significance of DNA polymerase I in in vivo processing of clustered DNA damage" [Mut. Res.: Fundam. Mol. Mech. Mutagen. 749 (2013) 9-15]
gan: Shikazono, N, et al.
Cyhoeddwyd: (2013)

Corrigendum to "Significance of DNA polymerase I in in vivo processing of clustered DNA damage" [Mut. Res.: Fundam. Mol. Mech. Mutagen. 749 (2013) 9-15]
gan: Shikazono, N, et al.
Cyhoeddwyd: (2013)

Exploring the mutagenic consequences of inflammation and DNA damage
gan: Kay, Jennifer Elizabeth, Ph. D. Massachusetts Institute of Technology
Cyhoeddwyd: (2018)

The mutagenic potential of 8-oxoG/single strand break-containing clusters depends on their relative positions
gan: Noguchi, M, et al.
Cyhoeddwyd: (2012)

The mutagenic potential of 8-oxoG/single strand break-containing clusters depends on their relative positions.
gan: Noguchi, M, et al.
Cyhoeddwyd: (2012)

Accelerated repair and reduced mutagenicity of DNA damage induced by cigarette smoke in human bronchial cells transfected with E.coli formamidopyrimidine DNA glycosylase.
gan: Mara Foresta, et al.
Cyhoeddwyd: (2014-01-01)

Significance of DNA polymerase I in in vivo processing of clustered DNA damage
gan: Shikazono, N, et al.
Cyhoeddwyd: (2013)

Significance of DNA polymerase I in in vivo processing of clustered DNA damage.
gan: Shikazono, N, et al.
Cyhoeddwyd: (2013)

Significance of DNA polymerase I in in vivo processing of clustered DNA damage (vol 749, pg 9, 2013)
gan: Shikazono, N, et al.
Cyhoeddwyd: (2013)

The role of DNA polymerase I in tolerating single-strand breaks generated at clustered DNA damage in Escherichia coli
gan: Naoya Shikazono, et al.
Cyhoeddwyd: (2024-08-01)

Biological consequences of radiation-induced DNA damage: relevance to radiotherapy.
gan: Lomax, M, et al.
Cyhoeddwyd: (2013)

Biological consequences of radiation-induced DNA damage: Relevance to radiotherapy
gan: Lomax, M, et al.
Cyhoeddwyd: (2013)

8-OxoA inhibits the incision of an AP site by the DNA glycosylases Fpg, Nth and the AP endonuclease HAP1.
gan: Lomax, M, et al.
Cyhoeddwyd: (2005)

The structural basis of specific base-excision repair by uracil-DNA glycosylase.
gan: Savva, R, et al.
Cyhoeddwyd: (1995)

DNA damage induced by the direct effect of He ion particles.
gan: Urushibara, A, et al.
Cyhoeddwyd: (2006)

Repair of oxidative base lesions within clustered DNA damage
gan: O'Neill, P, et al.
Cyhoeddwyd: (2002)

Evolutionary Origins of DNA Repair Pathways: Role of Oxygen Catastrophe in the Emergence of DNA Glycosylases
gan: Paulina Prorok, et al.
Cyhoeddwyd: (2021-06-01)

Aag DNA Glycosylase Promotes Alkylation-Induced Tissue Damage Mediated by Parp1
gan: Calvo, Jennifer A., et al.
Cyhoeddwyd: (2013)

Aag DNA glycosylase promotes alkylation-induced tissue damage mediated by Parp1.
gan: Jennifer A Calvo, et al.
Cyhoeddwyd: (2013-04-01)

Alkyladenine DNA glycosylase (Aag)-dependent cell-specific responses to alkylating agents
gan: Margulies, Carrie Marie
Cyhoeddwyd: (2016)

Chemical aspects of clustered DNA damage induction by ionising radiation.
gan: Lomax, M, et al.
Cyhoeddwyd: (2002)

Crystal structure of mimivirus uracil-DNA glycosylase.
gan: Eunju Kwon, et al.
Cyhoeddwyd: (2017-01-01)

Dissecting Highly Mutagenic Processing of Complex Clustered DNA Damage in Yeast <i>Saccharomyces cerevisiae</i>
gan: Stanislav G. Kozmin, et al.
Cyhoeddwyd: (2021-09-01)

Delayed repair of radiation induced clustered DNA damage: Friend or foe?
gan: Eccles, L, et al.
Cyhoeddwyd: (2011)

Delayed repair of radiation induced clustered DNA damage: friend or foe?
gan: Eccles, L, et al.
Cyhoeddwyd: (2011)

An engineered cell line lacking OGG1 and MUTYH glycosylases implicates the accumulation of genomic 8-oxoguanine as the basis for paraquat mutagenicity
gan: Tajai, Preechaya, et al.
Cyhoeddwyd: (2021)

Computational Study on DNA Repair: The Roles of Electrostatic Interactions Between Uracil-DNA Glycosylase (UDG) and DNA
gan: Yixin Xie, et al.
Cyhoeddwyd: (2021-08-01)

Direct measurement of the substrate preference of uracil-DNA glycosylase.
gan: Panayotou, G, et al.
Cyhoeddwyd: (1998)

The effect of sequence context on the activity of cytosine DNA glycosylases.
gan: Kimber, S, et al.
Cyhoeddwyd: (2015)

Potent pollen gene regulation by DNA glycosylases in maize
gan: Yibing Zeng, et al.
Cyhoeddwyd: (2024-09-01)

Uracil-DNA glycosylase efficiency is modulated by substrate rigidity
gan: Paul B. Orndorff, et al.
Cyhoeddwyd: (2023-03-01)

Radiation-induced damage in DNA
gan: O'Neill, P
Cyhoeddwyd: (2001)

A thermophilic 8-oxoguanine DNA glycosylase from Thermococcus barophiluss Ch5 is a new member of AGOG DNA glycosylase family
gan: Wang Lei, et al.
Cyhoeddwyd: (2022-06-01)

Contribution of base lesions to radiation-induced clustered DNA damage: implication for models of radiation response.
gan: Jenner, T, et al.
Cyhoeddwyd: (2001)

An AP site can protect against the mutagenic potential of 8-oxoG when present within a tandem clustered site in E. coli.
gan: Cunniffe, S, et al.
Cyhoeddwyd: (2007)

Clustered DNA damage, influence on damage excision by XRS5 nuclear extracts and Escherichia coli Nth and Fpg proteins.
gan: David-Cordonnier, M, et al.
Cyhoeddwyd: (2000)

Distinct Mechanisms of Target Search by Endonuclease VIII-like DNA Glycosylases
gan: Evgeniia A. Diatlova, et al.
Cyhoeddwyd: (2022-10-01)