The roles of specific glycosylases in determining the mutagenic consequences of clustered DNA base damage.

The roles of specific glycosylases in determining the mutagenic consequences of clustered DNA base damage.

The potential for genetic change arising from specific single types of DNA lesion has been thoroughly explored, but much less is known about the mutagenic effects of DNA lesions present in clustered damage sites. Localized clustering of damage is a hallmark of certain DNA-damaging agents, particular...

書誌詳細
主要な著者:	Shikazono, N, Pearson, C, O'Neill, P, Thacker, J
フォーマット:	Journal article
言語:	English
出版事項:	2006

類似資料

Enhanced mutagenic potential of 8-oxo-7,8-dihydroguanine when present within a clustered DNA damage site.
著者:: Pearson, C, 等
出版事項: (2004)

Processing of thymine glycol in a clustered DNA damage site: mutagenic or cytotoxic.
著者:: Bellon, S, 等
出版事項: (2009)

Mitochondrial inhibition of uracil-DNA glycosylase is not mutagenic
著者:: Singh Keshav K, 等
出版事項: (2004-12-01)

Biological consequences of potential repair intermediates of clustered base damage site in Escherichia coli.
著者:: Shikazono, N, 等
出版事項: (2009)

Corrigendum to "Significance of DNA polymerase I in in vivo processing of clustered DNA damage" [Mut. Res.: Fundam. Mol. Mech. Mutagen. 749 (2013) 9-15]
著者:: Shikazono, N, 等
出版事項: (2013)

Corrigendum to "Significance of DNA polymerase I in in vivo processing of clustered DNA damage" [Mut. Res.: Fundam. Mol. Mech. Mutagen. 749 (2013) 9-15]
著者:: Shikazono, N, 等
出版事項: (2013)

Exploring the mutagenic consequences of inflammation and DNA damage
著者:: Kay, Jennifer Elizabeth, Ph. D. Massachusetts Institute of Technology
出版事項: (2018)

The mutagenic potential of 8-oxoG/single strand break-containing clusters depends on their relative positions
著者:: Noguchi, M, 等
出版事項: (2012)

The mutagenic potential of 8-oxoG/single strand break-containing clusters depends on their relative positions.
著者:: Noguchi, M, 等
出版事項: (2012)

Accelerated repair and reduced mutagenicity of DNA damage induced by cigarette smoke in human bronchial cells transfected with E.coli formamidopyrimidine DNA glycosylase.
著者:: Mara Foresta, 等
出版事項: (2014-01-01)

Significance of DNA polymerase I in in vivo processing of clustered DNA damage
著者:: Shikazono, N, 等
出版事項: (2013)

Significance of DNA polymerase I in in vivo processing of clustered DNA damage.
著者:: Shikazono, N, 等
出版事項: (2013)

Significance of DNA polymerase I in in vivo processing of clustered DNA damage (vol 749, pg 9, 2013)
著者:: Shikazono, N, 等
出版事項: (2013)

The role of DNA polymerase I in tolerating single-strand breaks generated at clustered DNA damage in Escherichia coli
著者:: Naoya Shikazono, 等
出版事項: (2024-08-01)

Biological consequences of radiation-induced DNA damage: relevance to radiotherapy.
著者:: Lomax, M, 等
出版事項: (2013)

Biological consequences of radiation-induced DNA damage: Relevance to radiotherapy
著者:: Lomax, M, 等
出版事項: (2013)

8-OxoA inhibits the incision of an AP site by the DNA glycosylases Fpg, Nth and the AP endonuclease HAP1.
著者:: Lomax, M, 等
出版事項: (2005)

DNA damage induced by the direct effect of He ion particles.
著者:: Urushibara, A, 等
出版事項: (2006)

The structural basis of specific base-excision repair by uracil-DNA glycosylase.
著者:: Savva, R, 等
出版事項: (1995)

Repair of oxidative base lesions within clustered DNA damage
著者:: O'Neill, P, 等
出版事項: (2002)

Evolutionary Origins of DNA Repair Pathways: Role of Oxygen Catastrophe in the Emergence of DNA Glycosylases
著者:: Paulina Prorok, 等
出版事項: (2021-06-01)

Aag DNA Glycosylase Promotes Alkylation-Induced Tissue Damage Mediated by Parp1
著者:: Calvo, Jennifer A., 等
出版事項: (2013)

Aag DNA glycosylase promotes alkylation-induced tissue damage mediated by Parp1.
著者:: Jennifer A Calvo, 等
出版事項: (2013-04-01)

Alkyladenine DNA glycosylase (Aag)-dependent cell-specific responses to alkylating agents
著者:: Margulies, Carrie Marie
出版事項: (2016)

Chemical aspects of clustered DNA damage induction by ionising radiation.
著者:: Lomax, M, 等
出版事項: (2002)

Crystal structure of mimivirus uracil-DNA glycosylase.
著者:: Eunju Kwon, 等
出版事項: (2017-01-01)

Dissecting Highly Mutagenic Processing of Complex Clustered DNA Damage in Yeast <i>Saccharomyces cerevisiae</i>
著者:: Stanislav G. Kozmin, 等
出版事項: (2021-09-01)

Delayed repair of radiation induced clustered DNA damage: Friend or foe?
著者:: Eccles, L, 等
出版事項: (2011)

Delayed repair of radiation induced clustered DNA damage: friend or foe?
著者:: Eccles, L, 等
出版事項: (2011)

An engineered cell line lacking OGG1 and MUTYH glycosylases implicates the accumulation of genomic 8-oxoguanine as the basis for paraquat mutagenicity
著者:: Tajai, Preechaya, 等
出版事項: (2021)

Computational Study on DNA Repair: The Roles of Electrostatic Interactions Between Uracil-DNA Glycosylase (UDG) and DNA
著者:: Yixin Xie, 等
出版事項: (2021-08-01)

Direct measurement of the substrate preference of uracil-DNA glycosylase.
著者:: Panayotou, G, 等
出版事項: (1998)

The effect of sequence context on the activity of cytosine DNA glycosylases.
著者:: Kimber, S, 等
出版事項: (2015)

Potent pollen gene regulation by DNA glycosylases in maize
著者:: Yibing Zeng, 等
出版事項: (2024-09-01)

Uracil-DNA glycosylase efficiency is modulated by substrate rigidity
著者:: Paul B. Orndorff, 等
出版事項: (2023-03-01)

Computational and Experimental Druggability Assessment of Human DNA Glycosylases
著者:: Maurice Michel, 等
出版事項: (2019-07-01)

Radiation-induced damage in DNA
著者:: O'Neill, P
出版事項: (2001)

A thermophilic 8-oxoguanine DNA glycosylase from Thermococcus barophiluss Ch5 is a new member of AGOG DNA glycosylase family
著者:: Wang Lei, 等
出版事項: (2022-06-01)

DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes
著者:: Menghao Liu, 等
出版事項: (2021-07-01)

Contribution of base lesions to radiation-induced clustered DNA damage: implication for models of radiation response.
著者:: Jenner, T, 等
出版事項: (2001)