Evaluation of the non-toxic mutant of the diphtheria toxin K51E/E148K as carrier protein for meningococcal vaccines

Diphtheria toxin mutant CRM197 is a common carrier protein for glycoconjugate vaccines, which has been proven an effective protein vector for, among others, meningococcal carbohydrates. The wide-range use of this protein in massive vaccine production requires constant increase of production yields a...

全面介绍

书目详细资料
Main Authors: Pecetta, S, Vijayakrishnan, B, Romano, M, Proietti, D, Surdo, P, Balocchi, C, Mori, E, Davis, B, Berti, F
格式: Journal article
语言:English
出版: Elsevier 2016