Case-control studies of association in structured or admixed populations.
Case-control tests for association are an important tool for mapping complex-trait genes. But population structure can invalidate this approach, leading to apparent associations at markers that are unlinked to disease loci. Family-based tests of association can avoid this problem, but such studies a...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2001
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