Elongation dynamics of amyloid fibrils: a rugged energy landscape picture.

Elongation dynamics of amyloid fibrils: a rugged energy landscape picture.

Protein amyloid fibrils are a form of linear protein aggregates that are implicated in many neurodegenerative diseases. Here, we study the dynamics of amyloid fibril elongation by performing Langevin dynamic simulations on a coarse-grained model of peptides. Our simulation results suggest that the e...

Podrobná bibliografie
Hlavní autoři:	Lee, C, Loken, J, Jean, L, Vaux, D
Médium:	Journal article
Jazyk:	English
Vydáno:	2009

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