Endothelial nitric oxide synthase dysfunction in diabetic mice: importance of tetrahydrobiopterin in eNOS dimerisation.

Endothelial nitric oxide synthase dysfunction in diabetic mice: importance of tetrahydrobiopterin in eNOS dimerisation.

AIMS/HYPOTHESIS: Impaired nitric oxide (NO) bioactivity and increased superoxide (SO) production are characteristics of vascular endothelial dysfunction in diabetes. The underlying mechanisms remain unknown. In this regard, we investigated the role of tetrahydrobiopterin (BH4) bioavailability in reg...

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Dettagli Bibliografici
Autori principali:	Cai, S, Khoo, J, Mussa, S, Alp, N, Channon, K
Natura:	Journal article
Lingua:	English
Pubblicazione:	2005

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