Inadequate lung development and bronchial hyperplasia in mice with a targeted deletion in the Dutt1/Robo1 gene.
Chromosome 3 allele loss in preinvasive bronchial abnormalities and carcinogen-exposed, histologically normal bronchial epithelium indicates that it is an early, possibly the first, somatic genetic change in lung tumor development. Candidate tumor suppressor genes have been isolated from within dist...
المؤلفون الرئيسيون: | Xian, J, Clark, K, Fordham, R, Pannell, R, Rabbitts, T, Rabbitts, P |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2001
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مواد مشابهة
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Targeted disruption of the 3p12 gene, Dutt1/Robo1, predisposes mice to lung adenocarcinomas and lymphomas with methylation of the gene promoter.
حسب: Xian, J, وآخرون
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The role of Slit-Robo signaling in the generation, migration and morphological differentiation of cortical interneurons.
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The oncogenic LIM-only transcription factor Lmo2 regulates angiogenesis but not vasculogenesis in mice.
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DEATH AND DESPAIR IN THE POETRY OF TORU DUTT
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Tumorigenesis in mice with a fusion of the leukaemia oncogene Mll and the bacterial lacZ gene.
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