Inadequate lung development and bronchial hyperplasia in mice with a targeted deletion in the Dutt1/Robo1 gene.

Inadequate lung development and bronchial hyperplasia in mice with a targeted deletion in the Dutt1/Robo1 gene.

Chromosome 3 allele loss in preinvasive bronchial abnormalities and carcinogen-exposed, histologically normal bronchial epithelium indicates that it is an early, possibly the first, somatic genetic change in lung tumor development. Candidate tumor suppressor genes have been isolated from within dist...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak:	Xian, J, Clark, K, Fordham, R, Pannell, R, Rabbitts, T, Rabbitts, P
Formatua:	Journal article
Hizkuntza:	English
Argitaratua:	2001

Antzeko izenburuak

Targeted disruption of the 3p12 gene, Dutt1/Robo1, predisposes mice to lung adenocarcinomas and lymphomas with methylation of the gene promoter.
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Protocol for the selection of single-domain antibody fragments by third generation intracellular antibody capture.
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Intracellular antibody capture (IAC) methods for single domain antibodies.
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Functional intracellular antibody fragments do not require invariant intra-domain disulfide bonds.
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