Using Phenotypic Heterogeneity to Increase the Power of Genome-Wide Association Studies: Application to Age at Onset of Ischaemic Stroke Subphenotypes
Genome-wide association studies (GWAS) have been successful in identifying common variants related to complex disorders. However, some disorders have proved resistant to this strategy with few associations confirmed, despite evidence from twin and family studies of a genetic component. Sophisticated...
Main Authors: | Traylor, M, Bevan, S, Rothwell, P, Sudlow, C, Dichgans, M, Markus, H, Lewis, C |
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Format: | Journal article |
Language: | English |
Published: |
2013
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