Long chain n-alkyl compounds and oxa-derivatives thereof

Long chain N-alkyl amino and imino compounds, oxa-substituted derivatives thereof, and pharmaceutical compositions including such compounds are described. The long chain N-alkyl group is a C¿8?-C¿16? alkyl group. The long chain N-alkyl compounds and oxa-substituted derivatives thereof can be used in...

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Bibliographic Details
Main Authors: Zitzmann, N, Butters, T, Platt, F, Jacob, G, Picker, D, Carrouee, S, Fleet, G, Dwek, R, Durantel, D, Mehta, A, Block, T
Format: Patent
Language:English
Published: World Intellectual Property Organization 2016
Description
Summary:Long chain N-alkyl amino and imino compounds, oxa-substituted derivatives thereof, and pharmaceutical compositions including such compounds are described. The long chain N-alkyl group is a C¿8?-C¿16? alkyl group. The long chain N-alkyl compounds and oxa-substituted derivatives thereof can be used in the treatment of viral infections, in particular hepatitis B virus or hepatitis C virus, in a cell or an individual. For example, the long chain N-alkyl compounds or oxa-substituted derivatives thereof can be derived from piperidines, pyrrolidines, phenylamines, pyridines, pyrroles, or amino acids.