Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia.

Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia.

We describe an analysis of genome variation in 825 P. falciparum samples from Asia and Africa that identifies an unusual pattern of parasite population structure at the epicenter of artemisinin resistance in western Cambodia. Within this relatively small geographic area, we have discovered several d...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Miotto, O, Almagro-Garcia, J, Manske, M, Macinnis, B, Campino, S, Rockett, K, Amaratunga, C, Lim, P, Suon, S, Sreng, S, Anderson, J, Duong, S, Nguon, C, Chuor, C, Saunders, D, Se, Y, Lon, C, Fukuda, M, Amenga-Etego, L, Hodgson, A, Asoala, V, Imwong, M, Takala-Harrison, S, Nosten, F, Su, X
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	2013

Παρόμοια τεκμήρια

Genetic architecture of artemisinin-resistant Plasmodium falciparum
ανά: Miotto, O, κ.ά.
Έκδοση: (2015)

Spread of artemisinin resistance in Plasmodium falciparum malaria.
ανά: Ashley, E, κ.ά.
Έκδοση: (2014)

Artemisinin-resistant Plasmodium falciparum in Pursat province, western Cambodia: A parasite clearance rate study
ανά: Amaratunga, C, κ.ά.
Έκδοση: (2012)

Artemisinin-resistant Plasmodium falciparum in Pursat province, western Cambodia: a parasite clearance rate study.
ανά: Amaratunga, C, κ.ά.
Έκδοση: (2012)

Rapid and effective malaria control in Cambodia through mass administration of artemisinin-piperaquine
ανά: Seila Suon, κ.ά.
Έκδοση: (2010-02-01)

Plasmodium falciparum founder populations in western Cambodia have reduced artemisinin sensitivity in vitro.
ανά: Amaratunga, C, κ.ά.
Έκδοση: (2014)

Drug resistance. Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance.
ανά: Mok, S, κ.ά.
Έκδοση: (2015)

A molecular marker of artemisinin-resistant Plasmodium falciparum malaria.
ανά: Ariey, F, κ.ά.
Έκδοση: (2014)

A molecular marker of artemisinin-resistant Plasmodium falciparum malaria
ανά: Ariey, F, κ.ά.
Έκδοση: (2014)

Artemisinin resistance without pfkelch13 mutations in Plasmodium falciparum isolates from Cambodia.
ανά: Mukherjee, A, κ.ά.
Έκδοση: (2017)

Genetic markers associated with dihydroartemisinin–piperaquine failure in Plasmodium falciparum malaria in Cambodia: a genotype-phenotype association study
ανά: Kwiatkowski, D, κ.ά.
Έκδοση: (2016)

Reducing the spread of artemisinin resistant malaria through community-level directly observed therapy in Western of Cambodia
ανά: Say Chy, κ.ά.
Έκδοση: (2012-10-01)

Randomized trials of artemisinin-piperaquine, dihydroartemisinin-piperaquine phosphate and artemether-lumefantrine for the treatment of multi-drug resistant falciparum malaria in Cambodia-Thailand border area
ανά: Song Jianping, κ.ά.
Έκδοση: (2011-08-01)

Artemisinin resistance without pfkelch13 mutations in Plasmodium falciparum isolates from Cambodia
ανά: Angana Mukherjee, κ.ά.
Έκδοση: (2017-05-01)

Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance
ανά: Mok, S., κ.ά.
Έκδοση: (2016)

Optimising strategies for Plasmodium falciparum malaria elimination in Cambodia: primaquine, mass drug administration and artemisinin resistance.
ανά: Maude, R, κ.ά.
Έκδοση: (2012)

Dihydroartemisinin–piperaquine resistance in Plasmodium falciparum malaria in Cambodia: a multisite prospective cohort study
ανά: Amaratunga, C, κ.ά.
Έκδοση: (2016)

Dihydroartemisinin-piperaquine resistance in Plasmodium falciparum malaria in Cambodia: a multisite prospective cohort study.
ανά: Amaratunga, C, κ.ά.
Έκδοση: (2016)

Ex vivo susceptibility of Plasmodium falciparum to antimalarial drugs in western, northern, and eastern Cambodia, 2011-2012: association with molecular markers.
ανά: Lim, P, κ.ά.
Έκδοση: (2013)

Spatial and temporal epidemiology of clinical malaria in Cambodia 2004-2013
ανά: Maude, R, κ.ά.
Έκδοση: (2014)

Genetic loci associated with delayed clearance of Plasmodium falciparum following artemisinin treatment in Southeast Asia.
ανά: Takala-Harrison, S, κ.ά.
Έκδοση: (2013)

Exploring the contribution of candidate genes to artemisinin resistance in Plasmodium falciparum.
ανά: Imwong, M, κ.ά.
Έκδοση: (2010)

Independent emergence of artemisinin resistance mutations among Plasmodium falciparum in Southeast Asia.
ανά: Takala-Harrison, S, κ.ά.
Έκδοση: (2015)

Fitness loss under amino acid starvation in artemisinin-resistant Plasmodium falciparum isolates from Cambodia
ανά: Bunditvorapoom, D, κ.ά.
Έκδοση: (2018)

Population genomics and transcriptomics of Plasmodium falciparum in Cambodia and Vietnam uncover key components of the artemisinin resistance genetic background
ανά: Nayak, S, κ.ά.
Έκδοση: (2024)

Genomic epidemiology of artemisinin resistant malaria.
ανά: MalariaGEN Plasmodium falciparum Community Project, κ.ά.
Έκδοση: (2016)

High heritability of malaria parasite clearance rate indicates a genetic basis for artemisinin resistance in western Cambodia.
ανά: Anderson, T, κ.ά.
Έκδοση: (2010)

Origins of the current outbreak of multidrug-resistant malaria in southeast Asia: a retrospective genetic study
ανά: Amato, R, κ.ά.
Έκδοση: (2018)

Access to artemisinin combination therapy for malaria in remote areas of Cambodia.
ανά: Yeung, S, κ.ά.
Έκδοση: (2008)

Access to artemisinin combination therapy for malaria in remote areas of Cambodia
ανά: Socheat Doung, κ.ά.
Έκδοση: (2008-05-01)

Modulation of triple artemisinin-based combination therapy pharmacodynamics by Plasmodium falciparum genotype
ανά: Ansbro, MR, κ.ά.
Έκδοση: (2020)

Polymorphisms in Pvkelch12 and gene amplification of Pvplasmepsin4 in plasmodium vivax from Thailand, Lao PDR and Cambodia
ανά: Duanguppama, J, κ.ά.
Έκδοση: (2019)

Development of copy number assays for detection and surveillance of piperaquine resistance associated plasmepsin 2/3 copy number variation in Plasmodium falciparum
ανά: Ansbro, MR, κ.ά.
Έκδοση: (2020)

Population genomics and transcriptomics of Plasmodium falciparum in Cambodia and Vietnam uncover key components of the artemisinin resistance genetic background
ανά: Nayak, Sourav, κ.ά.
Έκδοση: (2025)

Population genomics and transcriptomics of Plasmodium falciparum in Cambodia and Vietnam uncover key components of the artemisinin resistance genetic background
ανά: Sourav Nayak, κ.ά.
Έκδοση: (2024-12-01)

Reduced artemisinin susceptibility of Plasmodium falciparum ring stages in western Cambodia.
ανά: Witkowski, B, κ.ά.
Έκδοση: (2013)

Functional analysis of Plasmodium falciparum subpopulations associated with artemisinin resistance in Cambodia
ανά: Ankit Dwivedi, κ.ά.
Έκδοση: (2017-12-01)

The last man standing is the most resistant: eliminating artemisinin-resistant malaria in Cambodia
ανά: Day Nicholas PJ, κ.ά.
Έκδοση: (2009-02-01)

Temporal evolution of sulfadoxine-pyrimethamine resistance genotypes and genetic diversity in response to a decade of increased interventions against Plasmodium falciparum in northern Ghana
ανά: Lucas N. Amenga-Etego, κ.ά.
Έκδοση: (2021-03-01)

Laboratory detection of artemisinin-resistant Plasmodium falciparum.
ανά: Chotivanich, K, κ.ά.
Έκδοση: (2014)