Antagonism of cytotoxic T-lymphocyte activation by soluble CD8.

Antagonism of cytotoxic T-lymphocyte activation by soluble CD8.

The CD8 co-receptor is important in the differentiation and selection of class I MHC-restricted T cells during thymic development, and in the activation of mature T lymphocytes in response to antigen. Here we show that soluble CD8alphaalpha receptor, despite an extremely low affinity for MHC, inhibi...

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Bibliographic Details
Main Authors:	Sewell, A, Gerth, U, Price, D, Purbhoo, M, Boulter, J, Gao, G, Bell, J, Phillips, R, Jakobsen, B
Format:	Journal article
Language:	English
Published:	1999

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