Transplantation tolerance: the big picture. Where do we stand, where should we go?

A major goal in organ transplantation has been to safely exploit the natural processes of immune tolerance in order to minimize the dose and duration of drug immunosuppression. In this commentary, I argue that we can learn from how tumours avoid rejection, to evolve a three-stage tolerance-inducing...

Полное описание

Библиографические подробности
Главный автор: Waldmann, H
Формат: Journal article
Язык:English
Опубликовано: Wiley 2017
Описание
Итог:A major goal in organ transplantation has been to safely exploit the natural processes of immune tolerance in order to minimize the dose and duration of drug immunosuppression. In this commentary, I argue that we can learn from how tumours avoid rejection, to evolve a three-stage tolerance-inducing strategy for transplanted tissues.