Transplantation tolerance: the big picture. Where do we stand, where should we go?

A major goal in organ transplantation has been to safely exploit the natural processes of immune tolerance in order to minimize the dose and duration of drug immunosuppression. In this commentary, I argue that we can learn from how tumours avoid rejection, to evolve a three-stage tolerance-inducing...

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Bibliografische gegevens
Hoofdauteur: Waldmann, H
Formaat: Journal article
Taal:English
Gepubliceerd in: Wiley 2017
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author Waldmann, H
author_facet Waldmann, H
author_sort Waldmann, H
collection OXFORD
description A major goal in organ transplantation has been to safely exploit the natural processes of immune tolerance in order to minimize the dose and duration of drug immunosuppression. In this commentary, I argue that we can learn from how tumours avoid rejection, to evolve a three-stage tolerance-inducing strategy for transplanted tissues.
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spelling oxford-uuid:bbf1532d-5d61-4282-a460-4f2f16a3b5e52022-03-27T05:20:47ZTransplantation tolerance: the big picture. Where do we stand, where should we go?Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:bbf1532d-5d61-4282-a460-4f2f16a3b5e5EnglishSymplectic Elements at OxfordWiley2017Waldmann, HA major goal in organ transplantation has been to safely exploit the natural processes of immune tolerance in order to minimize the dose and duration of drug immunosuppression. In this commentary, I argue that we can learn from how tumours avoid rejection, to evolve a three-stage tolerance-inducing strategy for transplanted tissues.
spellingShingle Waldmann, H
Transplantation tolerance: the big picture. Where do we stand, where should we go?
title Transplantation tolerance: the big picture. Where do we stand, where should we go?
title_full Transplantation tolerance: the big picture. Where do we stand, where should we go?
title_fullStr Transplantation tolerance: the big picture. Where do we stand, where should we go?
title_full_unstemmed Transplantation tolerance: the big picture. Where do we stand, where should we go?
title_short Transplantation tolerance: the big picture. Where do we stand, where should we go?
title_sort transplantation tolerance the big picture where do we stand where should we go
work_keys_str_mv AT waldmannh transplantationtolerancethebigpicturewheredowestandwhereshouldwego