The relative magnitude of transgene-specific adaptive immune responses induced by human and chimpanzee adenovirus vectors differs between laboratory animals and a target species.

The relative magnitude of transgene-specific adaptive immune responses induced by human and chimpanzee adenovirus vectors differs between laboratory animals and a target species.

Adenovirus vaccine vectors generated from new viral serotypes are routinely screened in pre-clinical laboratory animal models to identify the most immunogenic and efficacious candidates for further evaluation in clinical human and veterinary settings. Here, we show that studies in a laboratory speci...

書誌詳細
主要な著者:	Dicks, M, Guzman, E, Spencer, A, Gilbert, S, Charleston, B, Hill, A, Cottingham, M
フォーマット:	Journal article
言語:	English
出版事項:	Elsevier 2015

類似資料

Uncovering the mechanisms of adenovirus vector immunogenicity
著者:: Dicks, M, 等
出版事項: (2013)

A novel chimpanzee adenovirus vector with low human seroprevalence: improved systems for vector derivation and comparative immunogenicity.
著者:: Dicks, M, 等
出版事項: (2012)

Differential immunogenicity between HAdV-5 and chimpanzee adenovirus vector ChAdOx1 is independent of fiber and penton RGD loop sequences in mice
著者:: Dicks, M, 等
出版事項: (2015)

A novel chimpanzee adenovirus vector with low human seroprevalence: improved systems for vector derivation and comparative immunogenicity.
著者:: Matthew D J Dicks, 等
出版事項: (2012-01-01)

Immunogenicity and efficacy of a chimpanzee adenovirus-vectored Rift Valley fever vaccine in mice.
著者:: Warimwe, G, 等
出版事項: (2013)

Improved systems for generating and evaluating adenovirus vaccine vectors reveal differences in immunogenicity between vectors of different adenoviral species
著者:: Dicks, M, 等
出版事項: (2011)

Preventing spontaneous genetic rearrangements in the transgene cassettes of adenovirus vectors.
著者:: Cottingham, MG, 等
出版事項: (2012)

Preventing spontaneous genetic rearrangements in the transgene cassettes of adenovirus vectors
著者:: Cottingham, MG, 等
出版事項: (2011)

Prevalence of serum neutralizing antibodies against chimpanzee adenovirus 63 and human adenovirus 5 in Kenyan children, in the context of vaccine vector efficacy.
著者:: Dudareva, M, 等
出版事項: (2009)

Chimpanzee adenoviral vectors as vaccines for outbreak pathogens
著者:: Ewer (nee Russell), K, 等
出版事項: (2017)

Novel adenovirus vaccine vectors
著者:: Dicks, M
出版事項: (2013)

Chimpanzee adenovirus vaccine provides multispecies protection against Rift Valley Fever
著者:: Warimwe, G, 等
出版事項: (2016)

Chimpanzee adenoviral vectors as vaccines for outbreak pathogens
著者:: Katie Ewer, 等
出版事項: (2017-12-01)

Simian adenoviruses as vaccine vectors
著者:: Morris, S, 等
出版事項: (2016)

Simian adenoviruses as vaccine vectors
著者:: Morris, S, 等
出版事項: (2016)

Innate Immune Responses to Chimpanzee Adenovirus Vector 155 Vaccination in Mice and Monkeys
著者:: Catherine Collignon, 等
出版事項: (2020-11-01)

Chimpanzee adenovirus- and MVA-vectored respiratory syncytial virus vaccine is safe and immunogenic in adults.
著者:: Green, C, 等
出版事項: (2015)

Stability of Chimpanzee Adenovirus Vectored Vaccines (ChAdOx1 and ChAdOx2) in Liquid and Lyophilised Formulations
著者:: Adam Berg, 等
出版事項: (2021-10-01)

Transgene optimization, immunogenicity and in vitro efficacy of viral vectored vaccines expressing two alleles of Plasmodium falciparum AMA1.
著者:: Biswas, S, 等
出版事項: (2011)

A monovalent chimpanzee adenovirus Ebola vaccine — preliminary report
著者:: Rampling, T, 等
出版事項: (2015)

Manufacturing a chimpanzee adenovirus-vectored SARS-CoV-2 vaccine to meet global needs
著者:: Joe, CCD, 等
出版事項: (2021)

A monovalent chimpanzee adenovirus ebola vaccine boosted with MVA
著者:: Ewer (nee Russell), K, 等
出版事項: (2016)

T cells induced by recombinant chimpanzee adenovirus alone and in prime-boost regimens decrease chimeric EcoHIV/NDK challenge virus load.
著者:: Roshorm, Y, 等
出版事項: (2012)

Transcriptomic response and immunological responses to chimpanzee adenovirus- and MVA viral-vectored vaccines for RSV in healthy adults
著者:: Green, C, 等
出版事項: (2023)

Chimpanzee Adenovirus Antibodies in Humans, Sub-Saharan Africa
著者:: Zhiquan Xiang, 等
出版事項: (2006-10-01)

Correlates of Protection Against SIVmac251 Infection in Rhesus Macaques Immunized With Chimpanzee-Derived Adenovirus Vectors
著者:: Steven Tuyishime, 等
出版事項: (2018-05-01)

Mixed vector immunization with recombinant adenovirus and MVA can improve vaccine efficacy while decreasing antivector immunity.
著者:: Reyes-Sandoval, A, 等
出版事項: (2012)

Mixed vector immunization with recombinant adenovirus and MVA can improve vaccine efficacy while decreasing antivector immunity
著者:: Reyes-Sandoval, A, 等
出版事項: (2012)

Immune Thrombocytopenia Induced by the Chimpanzee Adenovirus-Vectored Vaccine against SARS-CoV-2 Infection
著者:: Po-Wei Liao, 等
出版事項: (2021-12-01)

Assessment of chimpanzee adenovirus serotype 63 neutralizing antibodies prior to evaluation of a candidate malaria vaccine regimen based on viral vectors.
著者:: Nébié, I, 等
出版事項: (2014)

A lyophilised formulation of chimpanzee adenovirus vector for long-term stability outside the deep-freeze cold chain
著者:: Frédéric Mathot, 等
出版事項: (2025-01-01)

Both chimpanzee adenovirus-vectored and DNA vaccines induced long-term immunity against Nipah virus infection
著者:: Mingqing Lu, 等
出版事項: (2023-11-01)

Clinical assessment of a novel recombinant simian adenovirus ChAdOx1 as a vectored vaccine expressing conserved influenza a antigens
著者:: Antrobus, R, 等
出版事項: (2014)

Clinical assessment of a novel recombinant simian adenovirus ChAdOx1 as a vectored vaccine expressing conserved Influenza A antigens.
著者:: Antrobus, R, 等
出版事項: (2014)

Protective CD8+ T-cell immunity to human malaria induced by chimpanzee adenovirus-MVA immunisation
著者:: Ewer, K, 等
出版事項: (2013)

Lichenoid drug reaction post-COVID vaccination with the modified chimpanzee adenovirus
著者:: Paola Garcia-Mendoza, 等
出版事項: (2022-01-01)

Cytokine Responses to Adenovirus and Adenovirus Vectors
著者:: Svetlana Atasheva, 等
出版事項: (2022-04-01)

Transgene optimization, immunogenicity and in vitro efficacy of viral vectored vaccines expressing two alleles of Plasmodium falciparum AMA1.
著者:: Sumi Biswas, 等
出版事項: (2011-01-01)

Seroprevalence of Neutralizing Antibodies against Human Adenovirus Type-5 and Chimpanzee Adenovirus Type-68 in Cancer Patients
著者:: Hua Zhao, 等
出版事項: (2018-03-01)

Improvement of BCG protective efficacy with a novel chimpanzee adenovirus and a modified vaccinia Ankara virus both expressing Ag85A
著者:: Stylianou, E, 等
出版事項: (2015)