The relative magnitude of transgene-specific adaptive immune responses induced by human and chimpanzee adenovirus vectors differs between laboratory animals and a target species.

The relative magnitude of transgene-specific adaptive immune responses induced by human and chimpanzee adenovirus vectors differs between laboratory animals and a target species.

Adenovirus vaccine vectors generated from new viral serotypes are routinely screened in pre-clinical laboratory animal models to identify the most immunogenic and efficacious candidates for further evaluation in clinical human and veterinary settings. Here, we show that studies in a laboratory speci...

书目详细资料
Main Authors:	Dicks, M, Guzman, E, Spencer, A, Gilbert, S, Charleston, B, Hill, A, Cottingham, M
格式:	Journal article
语言:	English
出版:	Elsevier 2015

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