Assessment of the neurotoxicity of parenteral artemisinin derivatives in mice.
In all experimental mammals tested (rats, dogs, primates), intramuscular injections of the oil-soluble antimalarial artemisinin derivatives artemether and arteether have produced an unusual pattern of selective damage to brain stem centers predominantly involved in auditory processing and vestibular...
Main Authors: | Nontprasert, A, Nosten-Bertrand, M, Pukrittayakamee, S, Vanijanonta, S, Angus, B, White, N |
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Format: | Journal article |
Language: | English |
Published: |
1998
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