Assessment of the neurotoxicity of parenteral artemisinin derivatives in mice.

In all experimental mammals tested (rats, dogs, primates), intramuscular injections of the oil-soluble antimalarial artemisinin derivatives artemether and arteether have produced an unusual pattern of selective damage to brain stem centers predominantly involved in auditory processing and vestibular...

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Détails bibliographiques
Auteurs principaux: Nontprasert, A, Nosten-Bertrand, M, Pukrittayakamee, S, Vanijanonta, S, Angus, B, White, N
Format: Journal article
Langue:English
Publié: 1998