Assessment of the neurotoxicity of parenteral artemisinin derivatives in mice.

In all experimental mammals tested (rats, dogs, primates), intramuscular injections of the oil-soluble antimalarial artemisinin derivatives artemether and arteether have produced an unusual pattern of selective damage to brain stem centers predominantly involved in auditory processing and vestibular...

Полное описание

Библиографические подробности
Главные авторы: Nontprasert, A, Nosten-Bertrand, M, Pukrittayakamee, S, Vanijanonta, S, Angus, B, White, N
Формат: Journal article
Язык:English
Опубликовано: 1998