A genome wide association study of Plasmodium falciparum susceptibility to 22 antimalarial drugs in Kenya

A genome wide association study of Plasmodium falciparum susceptibility to 22 antimalarial drugs in Kenya

BACKGROUND: Drug resistance remains a chief concern for malaria control. In order to determine the genetic markers of drug resistant parasites, we tested the genome-wide associations (GWA) of sequence-based genotypes from 35 Kenyan P. falciparum parasites with the activities of 22 antimalarial drugs...

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Huvudupphovsmän: Wendler, J, Okombo, J, Amato, R, Miotto, O, Kiara, S, Mwai, L, Pole, L, O'Brien, J, Manske, M, Alcock, D, Drury, E, Sanders, M, Oyola, S, Malangone, C, Jyothi, D, Miles, A, Rockett, K, Macinnis, B, Marsh, K, Bejon, P, Nzila, A, Kwiatkowski, D
Materialtyp: Journal article
Språk:English
Publicerad: Public Library of Science 2014

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