Structures of the EphA2 receptor at the membrane: Role of lipid interactions

Structures of the EphA2 receptor at the membrane: Role of lipid interactions

<p xmlns:etd="http://www.ouls.ox.ac.uk/ora/modsextensions">Ephs are transmembrane receptors that mediate cell-cell signaling. The N-terminal ectodomain binds ligands and enables receptor clustering, which activates the intracellular kinase. Relatively little is known about the functi...

Bibliográfalaš dieđut
Váldodahkkit:	Chavent, M, Seiradake, E, Jones, E, Sansom, M
Eará dahkkit:	Cancer Research UK
Materiálatiipa:	Journal article
Almmustuhtton:	Cell Press 2017

Geahča maid

Interactions of the EphA2 kinase domain with PIPs in membranes: implications for receptor function
Dahkki: Chavent, M, et al.
Almmustuhtton: (2018)

Ephrin Receptors (Eph): EphA1, EphA5, and EphA7 Expression in Uveal Melanoma—Associations with Clinical Parameters and Patient Survival
Dahkki: Malgorzata Gajdzis, et al.
Almmustuhtton: (2020-09-01)

Structurally encoded intraclass differences in EphA clusters drive distinct cell responses
Dahkki: Seiradake, E, et al.
Almmustuhtton: (2013)

Structurally encoded intraclass differences in EphA clusters drive distinct cell responses.
Dahkki: Seiradake, E, et al.
Almmustuhtton: (2013)

Targeting EphA2 in cancer
Dahkki: Ta Xiao, et al.
Almmustuhtton: (2020-08-01)

EphA2 Is a Therapy Target in EphA2-Positive Leukemias but Is Not Essential for Normal Hematopoiesis or Leukemia.
Dahkki: Sara Charmsaz, et al.
Almmustuhtton: (2015-01-01)

Preclinical and Toxicology Assessment of ALW-II-41-27, an Inhibitor of the Eph Receptor A2 (EphA2)
Dahkki: Theodore J. Kottom, et al.
Almmustuhtton: (2024-08-01)

Development of an In-House EphA2 ELISA for Human Serum and Measurement of Circulating Levels of EphA2 in Hypertensive Patients with Renal Dysfunction
Dahkki: Maki Murakoshi, et al.
Almmustuhtton: (2022-12-01)

Inhibition of VEGF-Dependent Multistage Carcinogenesis by Soluble EphA Receptors
Dahkki: Nikki Cheng, et al.
Almmustuhtton: (2003-09-01)

Upregulation of EphA Receptor Expression in the Injured Adult Rat Spinal Cord
Dahkki: Christopher A. Willson, et al.
Almmustuhtton: (2002-04-01)

EphA2 is a functional entry receptor for HCMV infection of glioblastoma cells.
Dahkki: Xiao-Dong Dong, et al.
Almmustuhtton: (2023-05-01)

Patterned Substrate of Mobile and Immobile Ligands to Probe EphA2 Receptor Clustering
Dahkki: Zhongwen Chen, et al.
Almmustuhtton: (2022-06-01)

EphrinA2 receptor (EphA2) is an invasion and intracellular signaling receptor for Chlamydia trachomatis.
Dahkki: Prema Subbarayal, et al.
Almmustuhtton: (2015-04-01)

#50. Investigating the role of EphA2 in breast cancer bone metastasis
Dahkki: Verra Ngwa, et al.
Almmustuhtton: (2024-04-01)

Role of EphA2 in host defense against oro-pharyngeal candidiasis
Dahkki: Ingar Olsen
Almmustuhtton: (2020-01-01)

Cancer-Related Mutations in the Sam Domains of EphA2 Receptor and Ship2 Lipid Phosphatase: A Computational Study
Dahkki: Marian Vincenzi, et al.
Almmustuhtton: (2024-02-01)

The EphA2 Receptor Regulates Invasiveness and Drug Sensitivity in Canine and Human Osteosarcoma Cells
Dahkki: Evelyn D. Harris, et al.
Almmustuhtton: (2024-07-01)

Review on cerebral malaria—Pathogenesis and role of EphA2 receptor in maintaining blood brain barrier integrity
Dahkki: Mohd Sayeed Shaikh, et al.
Almmustuhtton: (2024-06-01)

Synthesis and Structure-Activity Relationships of Amino Acid Conjugates of Cholanic Acid as Antagonists of the EphA2 Receptor
Dahkki: Alessio Lodola, et al.
Almmustuhtton: (2013-10-01)

Author Correction: The EphA2 receptor is activated through induction of distinct, ligand-dependent oligomeric structures
Dahkki: Deo R. Singh, et al.
Almmustuhtton: (2018-04-01)

EphA2 specific chimeric antigen receptor engineered T cells for the treatment of prostate cancer
Dahkki: Miaomiao Zhang, et al.
Almmustuhtton: (2024-12-01)

Comparative Analysis of Virtual Screening Approaches in the Search for Novel EphA2 Receptor Antagonists
Dahkki: Donatella Callegari, et al.
Almmustuhtton: (2015-09-01)

EphA2 contributes to disruption of the blood-brain barrier in cerebral malaria.
Dahkki: Thayer K Darling, et al.
Almmustuhtton: (2020-01-01)

Targeting the EphA2 pathway: could it be the way for bone sarcomas?
Dahkki: Giorgia Giordano, et al.
Almmustuhtton: (2024-09-01)

Theoretical Model of EphA2-Ephrin A1 Inhibition
Dahkki: Wiktoria Jedwabny, et al.
Almmustuhtton: (2018-07-01)

Optimizing EphA2-CAR T Cells for the Adoptive Immunotherapy of Glioma
Dahkki: Zhongzhen Yi, et al.
Almmustuhtton: (2018-06-01)

Interactions between EGFR and EphA2 promote tumorigenesis through the action of Ephexin1
Dahkki: Jeeho Kim, et al.
Almmustuhtton: (2022-06-01)

Drug-resistant cancer cell-derived exosomal EphA2 promotes breast cancer metastasis via the EphA2-Ephrin A1 reverse signaling
Dahkki: Zicong Gao, et al.
Almmustuhtton: (2021-04-01)

Probing the effect of clustering on EphA2 receptor signaling efficiency by subcellular control of ligand-receptor mobility
Dahkki: Zhongwen Chen, et al.
Almmustuhtton: (2021-08-01)

A novel pH-dependent membrane peptide that binds to EphA2 and inhibits cell migration
Dahkki: Daiane S Alves, et al.
Almmustuhtton: (2018-09-01)

The Expression of ephrinA1/ephA2 Receptor Increases in Chronic Rhinosinusitis and ephrinA1/ephA2 Signaling Affects Rhinovirus-Induced Innate Immunity in Human Sinonasal Epithelial Cells
Dahkki: Sang Hag Lee, et al.
Almmustuhtton: (2021-12-01)

Effective Tumor Targeting by EphA2-Agonist-Biotin-Streptavidin Conjugates
Dahkki: Parima Udompholkul, et al.
Almmustuhtton: (2021-06-01)

Regulation of the EphA2 receptor intracellular region by phosphomimetic negative charges in the kinase-SAM linker
Dahkki: Bernhard C. Lechtenberg, et al.
Almmustuhtton: (2021-12-01)

EphA2 Is a Neutrophil Receptor for Candida albicans that Stimulates Antifungal Activity during Oropharyngeal Infection
Dahkki: Marc Swidergall, et al.
Almmustuhtton: (2019-07-01)

EphA7 isoforms differentially regulate cortical dendrite development.
Dahkki: Carrie E Leonard, et al.
Almmustuhtton: (2020-01-01)

Direct interaction of receptor tyrosine kinases, EphA4 and PDGFRβ, plays an important role in the proliferation of neural stem cells
Dahkki: Chen QF, et al.
Almmustuhtton: (2017-07-01)

Retraction: The expression of ephrinA1/ephA2 receptor increases in chronic rhinosinusitis and ephrinA1/ephA2 signaling affects rhinovirus-induced innate immunity in human sinonasal epithelial cells
Dahkki: Frontiers Editorial Office
Almmustuhtton: (2024-07-01)

EphA1 receptor tyrosine kinase is localized to the nucleus in rhabdomyosarcoma from multiple species
Dahkki: Ronnie LaCombe, et al.
Almmustuhtton: (2022-10-01)

Unveiling the therapeutic promise of EphA2 in glioblastoma: a comprehensive review
Dahkki: Caohang Qiu, et al.
Almmustuhtton: (2024-09-01)

Engineering of monobody conjugates for human EphA2-specific optical imaging.
Dahkki: Min-A Kim, et al.
Almmustuhtton: (2017-01-01)