Analysis of transcription factor binding at cis-regulatory elements during blood development and differentiation

<p>The overall aim of this work is to understand how regulatory sequences (enhancers, promoters) are bound and interpreted by TFs during erythroid development and differentiation. This is becoming increasingly important as DNA sequence variants in enhancers may alter protein binding and conseq...

Full description

Bibliographic Details
Main Author: Suciu, MC
Other Authors: Higgs, D
Format: Thesis
Published: 2015