An AP site can protect against the mutagenic potential of 8-oxoG when present within a tandem clustered site in E. coli.
Ionizing radiation induces clustered DNA damaged sites, defined as two or more lesions formed within one or two helical turns of the DNA through passage of a single radiation track. It is now established that clustered DNA damage sites are found in cells and present a challenge to the repair machine...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2007
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