State-dependent protein-lipid interactions of a pentameric ligand-gated ion channel in a neuronal membrane

State-dependent protein-lipid interactions of a pentameric ligand-gated ion channel in a neuronal membrane

Pentameric ligand-gated ion channels (pLGICs) are receptor proteins that are sensitive to their membrane environment, but the mechanism for how lipids modulate function under physiological conditions in a state dependent manner is not known. The glycine receptor is a pLGIC whose structure has been r...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Dämgen, MA, Biggin, PC
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	Public Library of Science 2021

समान संसाधन

Investigating the function of a pentameric ligand-gated ion channel with molecular simulation
द्वारा: Dämgen, MA
प्रकाशित: (2019)

Lipid nanodisc scaffold and size alter the structure of a pentameric ligand-gated ion channel
द्वारा: Vikram Dalal, और अन्य
प्रकाशित: (2024-01-01)

Molecular simulations of hydrophobic gating of pentameric ligand gated ion channels: Insights into water and ions
द्वारा: Rao, S, और अन्य
प्रकाशित: (2021)

Signal Transduction at the Domain Interface of Prokaryotic Pentameric Ligand-Gated Ion Channels.
द्वारा: Carlo Bertozzi, और अन्य
प्रकाशित: (2016-03-01)

Decrypting the sequence of structural events during the gating transition of pentameric ligand-gated ion channels based on an interpolated elastic network model.
द्वारा: Wenjun Zheng, और अन्य
प्रकाशित: (2011-01-01)

Pentameric viral ion channels : from structure to function
द्वारा: Surya, Wahyu, और अन्य
प्रकाशित: (2015)

Modulation of ligand-gated ion channel function in insect neurones.
द्वारा: Pitman, R, और अन्य
प्रकाशित: (1997)

Cryo-EM structures of prokaryotic ligand-gated ion channel GLIC provide insights into gating in a lipid environment
द्वारा: Bharambe, Nikhil, और अन्य
प्रकाशित: (2024)

Cryo-EM structures of prokaryotic ligand-gated ion channel GLIC provide insights into gating in a lipid environment
द्वारा: Nikhil Bharambe, और अन्य
प्रकाशित: (2024-04-01)

The small hydrophobic protein of the human respiratory syncytial virus forms pentameric ion channels
द्वारा: Gan, Siok-Wan, और अन्य
प्रकाशित: (2013)

Simulation approaches to ion channel gating
द्वारा: Biggin, P, और अन्य
प्रकाशित: (2002)

Comment on “On the functional annotation of open-channel structures in the glycine receptor”
द्वारा: Dämgen, MA, और अन्य
प्रकाशित: (2020)

Modulation of insect ligand-gated ion channels
द्वारा: Pitman, R, और अन्य
प्रकाशित: (1999)

Computational methods to examine conformational changes and ligand-binding properties: Examples in neurobiology
द्वारा: Dämgen, M, और अन्य
प्रकाशित: (2018)

Discovery of lipid binding sites in a ligand-gated ion channel by integrating simulations and cryo-EM
द्वारा: Cathrine Bergh, और अन्य
प्रकाशित: (2024-01-01)

A Refined Open State of the Glycine Receptor Obtained via Molecular Dynamics Simulations
द्वारा: Dämgen, MA, और अन्य
प्रकाशित: (2019)

Frustration analysis of coronaviruses E protein variants in pentameric conformation
द्वारा: Koh, Hui Fen
प्रकाशित: (2023)

Recognition Functions of Pentameric C-Reactive Protein in Cardiovascular Disease
द्वारा: Alok Agrawal, और अन्य
प्रकाशित: (2014-01-01)

K+ channels: gating mechanisms and lipid interactions
द्वारा: Schmidt, M
प्रकाशित: (2013)

Sedimentation Equilibrium of a Small Oligomer-forming Membrane Protein: Effect of Histidine Protonation on Pentameric Stability
द्वारा: Surya, Wahyu, और अन्य
प्रकाशित: (2015)

Computational modelling and molecular dynamics simulations of ligand-gated ion channels
द्वारा: Amiri, S, और अन्य
प्रकाशित: (2006)

Ion channel gating: insights via molecular simulations.
द्वारा: Beckstein, O, और अन्य
प्रकाशित: (2003)

Molecular simulations and lipid-protein interactions: potassium channels and other membrane proteins.
द्वारा: Sansom, MS, और अन्य
प्रकाशित: (2005)

Computational investigation of voltage-gated sodium channel β3 subunit dynamics
द्वारा: Glass, WG, और अन्य
प्रकाशित: (2020)

Anionic lipids unlock the gates of select ion channels in the pacemaker family
द्वारा: Schmidpeter, PAM, और अन्य
प्रकाशित: (2022)

Channel gating: twist to open.
द्वारा: Biggin, P, और अन्य
प्रकाशित: (2001)

Microelectrode Arrays Measure Blocking of Voltage‐Gated Calcium Ion Channels on Supported Lipid Bilayers Derived from Primary Neurons
द्वारा: Zixuan Lu, और अन्य
प्रकाशित: (2024-07-01)

The cys-loop ligand-gated ion channel gene superfamily of the nematode, Caenorhabditis elegans.
द्वारा: Jones, A, और अन्य
प्रकाशित: (2008)

Coronavirus E protein forms ion channels with functionally and structurally-involved membrane lipids
द्वारा: Nieto-Torres, Jose L., और अन्य
प्रकाशित: (2013)

When is a hydrophobic gate not a hydrophobic gate?
द्वारा: Seiferth, D, और अन्य
प्रकाशित: (2022)

The cys-loop ligand-gated ion channel gene superfamily of the parasitoid wasp, Nasonia vitripennis.
द्वारा: Jones, A, और अन्य
प्रकाशित: (2010)

Protein crowding and lipid complexity influence the nanoscale dynamic organization of ion channels in cell membranes
द्वारा: Duncan, A, और अन्य
प्रकाशित: (2017)

Voltage-gated ion channels.
द्वारा: Sands, Z, और अन्य
प्रकाशित: (2005)

Hydrophobic gating in ion channels.
द्वारा: Aryal, P, और अन्य
प्रकाशित: (2015)

Molecular dynamics of synthetic ion channels in a lipid membrane
द्वारा: Randa, H, और अन्य
प्रकाशित: (2000)

Membrane protein simulations: ion channels and bacterial outer membrane proteins.
द्वारा: Domene, C, और अन्य
प्रकाशित: (2003)

The PM2 virion has a novel organization with an internal membrane and pentameric receptor binding spikes.
द्वारा: Huiskonen, J, और अन्य
प्रकाशित: (2004)

Probing membrane protein-lipid interactions
द्वारा: Agasid, MT, और अन्य
प्रकाशित: (2021)

The gating mechanism in cyclic nucleotide-gated ion channels
द्वारा: Mazzolini, M, और अन्य
प्रकाशित: (2018)

Membrane proteins: Aquaporins--channels without ions.
द्वारा: Sansom, MS, और अन्य
प्रकाशित: (2001)