Chloroplast ubiquitin E3 ligase SP1: Does it really function in peroxisomes?
Pan et al. (2016) presented evidence that the plant ubiquitin E3 ligase SP1 directs proteasome-mediated regulation of the peroxisomal protein import machinery. This was surprising, as SP1 was originally identified as a chloroplast outer envelope-localized regulator of the chloroplast protein import...
| Principais autores: | , , |
|---|---|
| Formato: | Journal article |
| Publicado em: |
American Society of Plant Biologists
2017
|
| _version_ | 1826293858235842560 |
|---|---|
| author | Jarvis, RP Ling, Q Li, N |
| author_facet | Jarvis, RP Ling, Q Li, N |
| author_sort | Jarvis, RP |
| collection | OXFORD |
| description | Pan et al. (2016) presented evidence that the plant ubiquitin E3 ligase SP1 directs proteasome-mediated regulation of the peroxisomal protein import machinery. This was surprising, as SP1 was originally identified as a chloroplast outer envelope-localized regulator of the chloroplast protein import machinery (Ling et al., 2012; Ling and Jarvis, 2015), and there was nothing in the original datasets to suggest functions elsewhere in the cell. It was also difficult to understand how a key regulator of chloroplast protein import, which mediates nuanced and selective effects during development and under stress (Ling et al., 2012; Ling and Jarvis, 2015), could additionally operate in a second organelle with a very different protein import system (Léon et al., 2006). We sought to address these issues by conducting additional experimental analyses. |
| first_indexed | 2024-03-07T03:36:38Z |
| format | Journal article |
| id | oxford-uuid:bc8396b9-19d2-42f1-bfcb-14b80c2883c5 |
| institution | University of Oxford |
| last_indexed | 2024-03-07T03:36:38Z |
| publishDate | 2017 |
| publisher | American Society of Plant Biologists |
| record_format | dspace |
| spelling | oxford-uuid:bc8396b9-19d2-42f1-bfcb-14b80c2883c52022-03-27T05:24:56ZChloroplast ubiquitin E3 ligase SP1: Does it really function in peroxisomes?Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:bc8396b9-19d2-42f1-bfcb-14b80c2883c5Symplectic Elements at OxfordAmerican Society of Plant Biologists2017Jarvis, RPLing, QLi, NPan et al. (2016) presented evidence that the plant ubiquitin E3 ligase SP1 directs proteasome-mediated regulation of the peroxisomal protein import machinery. This was surprising, as SP1 was originally identified as a chloroplast outer envelope-localized regulator of the chloroplast protein import machinery (Ling et al., 2012; Ling and Jarvis, 2015), and there was nothing in the original datasets to suggest functions elsewhere in the cell. It was also difficult to understand how a key regulator of chloroplast protein import, which mediates nuanced and selective effects during development and under stress (Ling et al., 2012; Ling and Jarvis, 2015), could additionally operate in a second organelle with a very different protein import system (Léon et al., 2006). We sought to address these issues by conducting additional experimental analyses. |
| spellingShingle | Jarvis, RP Ling, Q Li, N Chloroplast ubiquitin E3 ligase SP1: Does it really function in peroxisomes? |
| title | Chloroplast ubiquitin E3 ligase SP1: Does it really function in peroxisomes? |
| title_full | Chloroplast ubiquitin E3 ligase SP1: Does it really function in peroxisomes? |
| title_fullStr | Chloroplast ubiquitin E3 ligase SP1: Does it really function in peroxisomes? |
| title_full_unstemmed | Chloroplast ubiquitin E3 ligase SP1: Does it really function in peroxisomes? |
| title_short | Chloroplast ubiquitin E3 ligase SP1: Does it really function in peroxisomes? |
| title_sort | chloroplast ubiquitin e3 ligase sp1 does it really function in peroxisomes |
| work_keys_str_mv | AT jarvisrp chloroplastubiquitine3ligasesp1doesitreallyfunctioninperoxisomes AT lingq chloroplastubiquitine3ligasesp1doesitreallyfunctioninperoxisomes AT lin chloroplastubiquitine3ligasesp1doesitreallyfunctioninperoxisomes |