Characterization of human urinary metabolites of the antimalarial piperaquine.

Five metabolites of the antimalarial piperaquine (PQ) (1,3-bis-[4-(7-chloroquinolyl-4)-piperazinyl-1]-propane) have been identified and their molecular structures characterized. After a p.o. dose of dihydroartemisinin-piperaquine, urine collected over 16 h from two healthy subjects was analyzed usin...

詳細記述

書誌詳細
主要な著者: Tarning, J, Bergqvist, Y, Day, N, Bergquist, J, Arvidsson, B, White, N, Ashton, M, Lindegårdh, N
フォーマット: Journal article
言語:English
出版事項: 2006