Quantitative mass spectrometry reveals dynamics of factor-inhibiting hypoxia-inducible factor-catalyzed hydroxylation.

Quantitative mass spectrometry reveals dynamics of factor-inhibiting hypoxia-inducible factor-catalyzed hydroxylation.

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The asparaginyl hydroxylase, factor-inhibiting hypoxia-inducible factor (HIF), is central to the oxygen-sensing pathway that controls the activity of HIF. Factor-inhibiting HIF (FIH) also catalyzes the hydroxylation of a large set of proteins that share a structural motif termed the ankyrin repeat d...

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Détails bibliographiques
Auteurs principaux:	Singleton, R, Trudgian, D, Fischer, R, Kessler, B, Ratcliffe, P, Cockman, M
Format:	Journal article
Langue:	English
Publié:	2011

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