Exploring conformational transitions and free-energy profiles of proton-coupled oligopeptide transporters

Exploring conformational transitions and free-energy profiles of proton-coupled oligopeptide transporters

Proteins involved in peptide uptake and transport belong to the proton-coupled oligopeptide transporter (POT) family. Crystal structures of POT family members reveal a common fold consisting of two domains of six transmembrane α helices that come together to form a "V" shaped transporter w...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Batista, MRB, Watts, A, Costa-Filho, AJ
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	American Chemical Society 2019

Eitemau Tebyg

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Molecular Dynamics Simulations Reveal the Proton:Peptide Coupling Mechanism in the Bacterial Proton-Coupled Oligopeptide Transporter YbgH
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Molecular Insights to the Structure-Interaction Relationships of Human Proton-Coupled Oligopeptide Transporters (PepTs)
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Structural insights into substrate recognition in proton-dependent oligopeptide transporters
gan: Quistgaard, Esben M., et al.
Cyhoeddwyd: (2013)

Biochemical and biophysical studies of the prokaryotic proton dependent oligopeptide transporters
gan: Solcan, N
Cyhoeddwyd: (2013)

Accurate Prediction of Ligand Affinities for a Proton-Dependent Oligopeptide Transporter
gan: Newstead, S, et al.
Cyhoeddwyd: (2016)

Conformational flexibility of GRASPs and their constituent PDZ subdomains reveals structural basis of their promiscuous interactome
gan: Mendes, LFS, et al.
Cyhoeddwyd: (2020)

Improving oral drug delivery: computational studies of proton dependent oligopeptide transporters
gan: Samsudin, M
Cyhoeddwyd: (2015)

Towards a structural understanding of drug and peptide transport within the proton-dependent oligopeptide transporter (POT) family.
gan: Newstead, S
Cyhoeddwyd: (2011)

Towards a Structural Understanding of Alternating Access within the Proton Dependent Oligopeptide Transporter (POT) Family
gan: Newstead, S
Cyhoeddwyd: (2012)

Characterization of the PT Clade of Oligopeptide Transporters in Rice
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Cyhoeddwyd: (2008-11-01)

Randomizing of Oligopeptide Conformations by Nearest Neighbor Interactions between Amino Acid Residues
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Cyhoeddwyd: (2022-05-01)

Structures in multiple conformations reveal distinct transition metal and proton pathways in an Nramp transporter
gan: Aaron T Bozzi, et al.
Cyhoeddwyd: (2019-02-01)

Alternating access mechanism in the POT family of oligopeptide transporters.
gan: Solcan, N, et al.
Cyhoeddwyd: (2012)

Alternating access mechanism in the POT family of oligopeptide transporters
gan: Solcan, N, et al.
Cyhoeddwyd: (2012)

Analyses of the oligopeptide transporter gene family in poplar and grape
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Cyhoeddwyd: (2011-09-01)

Functional characterization of oligopeptide transporter 1 of dairy cows
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Theoretical and NMR Conformational Studies of β-Proline Oligopeptides With Alternating Chirality of Pyrrolidine Units
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Long-Distance Protonation-Conformation Coupling in Phytochrome Species
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Electrophysiological analysis of the epithelial H+/oligopeptide transporter, PepT1
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Cyclic di-AMP traps proton-coupled K+ transporters of the KUP family in an inward-occluded conformation
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Process for making oligopeptides
gan: Jiang, S
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Concentration-Driven Assembly and Sol–Gel Transition of π‑Conjugated Oligopeptides
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Cyhoeddwyd: (2017-08-01)

Molecular and structural basis of oligopeptide recognition by the Ami transporter system in pneumococci.
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Transport Deficiency Is the Molecular Basis of Candida albicans Resistance to Antifungal Oligopeptides
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Diversity of Oligopeptide Transport in Yeast and Its Impact on Adaptation to Winemaking Conditions
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Crystal structure of a prokaryotic homologue of the mammalian oligopeptide-proton symporters, PepT1 and PepT2.
gan: Newstead, S, et al.
Cyhoeddwyd: (2011)

Crystal structure of a prokaryotic homologue of the mammalian oligopeptide-proton symporters, PepT1 and PepT2
gan: Newstead, S, et al.
Cyhoeddwyd: (2011)

Exploring conformational equilibria of a heterodimeric ABC transporter
gan: M Hadi Timachi, et al.
Cyhoeddwyd: (2017-01-01)

The conformation of an inhibitor bound to the gastric proton pump.
gan: Middleton, D, et al.
Cyhoeddwyd: (1997)

Impact of nanodisc lipid composition on cell-free expression of proton-coupled folate transporter
gan: Hoa Quynh Do, et al.
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Two mechanisms of membrane digestion: enzymatic-transport ensemble exists for oligopeptides as well
gan: S. T. Metelsky, et al.
Cyhoeddwyd: (2011-05-01)

An oligopeptide transporter of Mycobacterium tuberculosis regulates cytokine release and apoptosis of infected macrophages.
gan: Arunava Dasgupta, et al.
Cyhoeddwyd: (2010-01-01)

Coupled free fermion conformal field theories
gan: Peter Bouwknegt, et al.
Cyhoeddwyd: (2024-08-01)

Identification of an oligopeptide binding to hepatocellular carcinoma.
gan: Shimizu, A, et al.
Cyhoeddwyd: (2006)

SYNTHESIS OF OLIGOPEPTIDES OF DEFINED FRAGMENT COMPOSITION
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The mechanism of mammalian proton-coupled peptide transporters
gan: Simon M Lichtinger, et al.
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Proton-control of transitions in an amino-acid transporter
gan: Wu, Z, et al.
Cyhoeddwyd: (2019)

Proton-control of transitions in an amino-acid transporter
gan: Wu, Z, et al.
Cyhoeddwyd: (2019)

Exploring the conformal transition from above and below
gan: Alex Pomarol, et al.
Cyhoeddwyd: (2024-08-01)