Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans.

Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans.

OBJECTIVE Recent genome-wide association studies have revealed loci associated with glucose and insulin-related traits. We aimed to characterize 19 such loci using detailed measures of insulin processing, secretion, and sensitivity to help elucidate their role in regulation of glucose control, insul...

Full description

Bibliographic Details
Main Authors: Ingelsson, E, Langenberg, C, Hivert, M, Prokopenko, I, Lyssenko, V, Dupuis, J, Mägi, R, Sharp, S, Jackson, A, Assimes, T, Shrader, P, Knowles, J, Zethelius, B, Abbasi, F, Bergman, R, Bergmann, A, Berne, C, Boehnke, M, Bonnycastle, L, Bornstein, SR, Buchanan, T, Bumpstead, S, Böttcher, Y, Chines, P, Collins, F, Cooper, C, Dennison, E, Erdos, MR, Ferrannini, E, Fox, C, Graessler, J, Hao, K, Isomaa, B, Jameson, K, Kovacs, P, Kuusisto, J, Laakso, M, Ladenvall, C, Mohlke, K, Morken, M, Narisu, N, Nathan, D, Pascoe, L, Payne, F, Petrie, JR, Sayer, A, Schwarz, P, Scott, L, Stringham, H, Stumvoll, M, Swift, A, Syvänen, A, Tuomi, T, Tuomilehto, J, Tönjes, A, Valle, T, Williams, G, Lind, L, Barroso, I, Quertermous, T, Walker, M, Wareham, N, Meigs, J, McCarthy, M, Groop, L, Watanabe, R, Florez, J
Format: Conference item
Published: 2010

Similar Items

Similar Items