Centrioles generate a local pulse of Polo/PLK1 activity to initiate mitotic centrosome assembly

Centrioles generate a local pulse of Polo/PLK1 activity to initiate mitotic centrosome assembly

Mitotic centrosomes are formed when centrioles start to recruit large amounts of pericentriolar material (PCM) around themselves in preparation for mitosis. This centrosome “maturation” requires the centrioles and also Polo/PLK1 protein kinase. The PCM comprises several hundred proteins and, in Dros...

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Bibliographic Details
Main Authors:	Wong, S-S, Wilmott, Z, Alvarez-Rodrigo, I, Zhou, FY, Chau, K-Y, Goriely, A, Raff, J
Format:	Journal article
Language:	English
Published:	EMBO Press 2022

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