High-risk melanoma with nodal involvement in a young woman.

BACKGROUND: An 18-year-old female presented to her General Practitioner with a bleeding mole on her back. The mole had been present since childhood but had started to bleed in the past month. She was otherwise asymptomatic with no relevant previous medical history. Physical examination revealed a 1...

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Autores principales: Khan, O, Middleton, M
Formato: Journal article
Lenguaje:English
Publicado: 2006
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author Khan, O
Middleton, M
author_facet Khan, O
Middleton, M
author_sort Khan, O
collection OXFORD
description BACKGROUND: An 18-year-old female presented to her General Practitioner with a bleeding mole on her back. The mole had been present since childhood but had started to bleed in the past month. She was otherwise asymptomatic with no relevant previous medical history. Physical examination revealed a 1.5 cm 1.7 cm pigmented lesion on the left aspect of the patient's upper back. There was no palpable lymphadenopathy. INVESTIGATIONS: Physical examination, excision biopsy, sentinel lymph node biopsy, CT scan of chest, abdomen and pelvis. DIAGNOSIS: Stage IIIB (T3bN2aM0) focally ulcerated, nodular malignant melanoma (Breslow depth 2.5 mm, Clark's level IV). MANAGEMENT: Wide re-excision, completion dissection of the left axillary lymph node, adjuvant high-dose interferon with maintenance interferon.
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spelling oxford-uuid:bcc7b96b-066c-4ddc-9b92-0698de631c2d2022-03-27T05:26:53ZHigh-risk melanoma with nodal involvement in a young woman.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:bcc7b96b-066c-4ddc-9b92-0698de631c2dEnglishSymplectic Elements at Oxford2006Khan, OMiddleton, M BACKGROUND: An 18-year-old female presented to her General Practitioner with a bleeding mole on her back. The mole had been present since childhood but had started to bleed in the past month. She was otherwise asymptomatic with no relevant previous medical history. Physical examination revealed a 1.5 cm 1.7 cm pigmented lesion on the left aspect of the patient's upper back. There was no palpable lymphadenopathy. INVESTIGATIONS: Physical examination, excision biopsy, sentinel lymph node biopsy, CT scan of chest, abdomen and pelvis. DIAGNOSIS: Stage IIIB (T3bN2aM0) focally ulcerated, nodular malignant melanoma (Breslow depth 2.5 mm, Clark's level IV). MANAGEMENT: Wide re-excision, completion dissection of the left axillary lymph node, adjuvant high-dose interferon with maintenance interferon.
spellingShingle Khan, O
Middleton, M
High-risk melanoma with nodal involvement in a young woman.
title High-risk melanoma with nodal involvement in a young woman.
title_full High-risk melanoma with nodal involvement in a young woman.
title_fullStr High-risk melanoma with nodal involvement in a young woman.
title_full_unstemmed High-risk melanoma with nodal involvement in a young woman.
title_short High-risk melanoma with nodal involvement in a young woman.
title_sort high risk melanoma with nodal involvement in a young woman
work_keys_str_mv AT khano highriskmelanomawithnodalinvolvementinayoungwoman
AT middletonm highriskmelanomawithnodalinvolvementinayoungwoman