Linker histone H1.2 directs genome-wide chromatin association of the retinoblastoma tumor suppressor protein and facilitates its function

Linker histone H1.2 directs genome-wide chromatin association of the retinoblastoma tumor suppressor protein and facilitates its function

The retinoblastoma tumor suppressor protein pRb is a master regulator of cellular proliferation, principally through interaction with E2F and regulation of E2F target genes. Here, we describe the H1.2 linker histone as a major pRb interaction partner. We establish that H1.2 and pRb are found in a ch...

书目详细资料
Main Authors:	Munro, S, Hookway, E, Floderer, M, Carr, S, Konietzny, R, Kessler, B, Oppermann, U, La Thangue, N
格式:	Journal article
语言:	English
出版:	Elsevier 2017

相似书籍

Linker Histone H1.2 Directs Genome-wide Chromatin Association of the Retinoblastoma Tumor Suppressor Protein and Facilitates Its Function
由: Shonagh Munro, et al.
出版: (2017-06-01)

Interplay between lysine methylation and Cdk phosphorylation in growth control by the retinoblastoma protein.
由: Carr, S, et al.
出版: (2011)

Interplay between lysine methylation and Cdk phosphorylation in growth control by the retinoblastoma protein.
由: Carr, S, et al.
出版: (2011)

Tudor-domain protein PHF20L1 reads lysine methylated retinoblastoma tumour suppressor protein
由: Carr, S, et al.
出版: (2017)

Linker histone epitopes are hidden by in situ higher-order chromatin structure
由: Vladimir B. Teif, et al.
出版: (2020-06-01)

Anticancer Plant Secondary Metabolites Induce Linker Histone Depletion from Chromatin
由: Olga Vlasova, et al.
出版: (2024-08-01)

Linker histones are fine-scale chromatin architects modulating developmental decisions in Arabidopsis
由: Kinga Rutowicz, et al.
出版: (2019-08-01)

Molecular and Cellular Functions of the Linker Histone H1.2
由: Shuting Lai, et al.
出版: (2022-01-01)

Biochemical and biophysical investigations of the dependences of chromatin/nucleosome structure on linker histone and histone H4K20-trimethylation
由: Wang, Sai
出版: (2018)

Lysine methylation-dependent binding of 53BP1 to the pRb tumor suppressor.
由: Carr, S, et al.
出版: (2014)

Lysine methylation regulates the pRb tumour suppressor protein.
由: Munro, S, et al.
出版: (2010)

CHROMATIN ACCESSIBILITY TO DNA MINOR GROOVE LIGANDS IN VITRO: ROLE OF LINKER HISTONES AND AMINO-TERMINAL DOMAINS OF OCT AMER HISTONES
由: R. Foderà, et al.
出版: (2000-04-01)

Linking H1 with chromatin and growth control.
由: Munro, S, et al.
出版: (2017)

Retinoblastoma tumor suppressor gene: An overview
由: Sunila Thomas, et al.
出版: (2012-01-01)

Human linker histones: interplay between phosphorylation and O-β-GlcNAc to mediate chromatin structural modifications
由: Nazar Shazia, et al.
出版: (2011-07-01)

Linker histone variant H1t is closely associated with repressed repeat-element chromatin domains in pachytene spermatocytes
由: Iyer Aditya Mahadevan, et al.
出版: (2020-03-01)

Linking H1 with chromatin and growth control
由: Shonagh Munro, et al.
出版: (2017-11-01)

Genome-wide characterization and evolutionary analysis of linker histones in castor bean (Ricinus communis)
由: Jiayu Guo, et al.
出版: (2022-10-01)

Proapoptotic Function of the Retinoblastoma Tumor Suppressor Protein
由: Ianari, Alessandra, et al.
出版: (2014)

Targeting Retinoblastoma tumour suppressor deficiency in Leiomyosarcoma
由: Sechi, I
出版: (2024)

The Linker Histone H1.2 Is an Intermediate in the Apoptotic Response to Cytokine Deprivation in T-Effectors
由: Megha Garg, et al.
出版: (2014-01-01)

Arabidopsis homologs of retinoblastoma-associated protein 46/48 associate with a histone deacetylase to act redundantly in chromatin silencing.
由: Xiaofeng Gu, et al.
出版: (2011-11-01)

Linker histone H1.8 inhibits chromatin binding of condensins and DNA topoisomerase II to tune chromosome length and individualization
由: Pavan Choppakatla, et al.
出版: (2021-08-01)

An all-atom model of the chromatin fiber containing linker histones reveals a versatile structure tuned by the nucleosomal repeat length.
由: Hua Wong, et al.
出版: (2007-01-01)

Cdh11 acts as a tumor suppressor in a murine retinoblastoma model by facilitating tumor cell death.
由: Mellone N Marchong, et al.
出版: (2010-04-01)

Linker histone variant H1.2 is a brake on white adipose tissue browning
由: Yangmian Yuan, et al.
出版: (2023-07-01)

Linker histone H1.2 and H1.4 affect the neutrophil lineage determination
由: Gabriel Sollberger, et al.
出版: (2020-05-01)

Pleiotropic effect of somatic mutations in the E2F subunit DP-1 gene in human cancer.
由: Munro, S, et al.
出版: (2014)

Pleiotropic effect of somatic mutations in the E2F subunit DP-1 gene in human cancer
由: Munro, S, et al.
出版: (2014)

The Retinoblastoma Tumor Suppressor Transcriptionally Represses Pak1 in Osteoblasts.
由: Bernadette Sosa-García, et al.
出版: (2015-01-01)

The retinoblastoma tumor suppressor regulates a xenobiotic detoxification pathway.
由: Maria Teresa Sáenz Robles, et al.
出版: (2011-01-01)

The tumour suppressor brain tumour (Brat) regulates linker histone dBigH1 expression in the Drosophila female germline and the early embryo
由: Paula Climent-Cantó, et al.
出版: (2021-05-01)

Histone H3 core domain in chromatin with different DNA linker lengths studied by 1H-Detected solid-state NMR spectroscopy
由: Sean T. Smrt, et al.
出版: (2023-01-01)

Pan-cancer atlas of somatic core and linker histone mutations
由: Erin R. Bonner, et al.
出版: (2023-08-01)

Destabilization of the outer and inner mitochondrial membranes by core and linker histones.
由: Annunziata Cascone, et al.
出版: (2012-01-01)

Characterization of Medusavirus encoded histones reveals nucleosome-like structures and a unique linker histone
由: Chelsea M. Toner, et al.
出版: (2024-10-01)

Androgen Receptor Tumor Suppressor Function Is Mediated by Recruitment of Retinoblastoma Protein
由: Shuai Gao, et al.
出版: (2016-10-01)

Genome-wide analysis of interactions between ATP-dependent chromatin remodeling and histone modifications
由: Wang Jiang, et al.
出版: (2009-07-01)

Chromatin structure-dependent histone incorporation revealed by a genome-wide deposition assay
由: Hiroaki Tachiwana, et al.
出版: (2021-05-01)

Dynamic distribution of linker histone H1.5 in cellular differentiation.
由: Jing-Yu Li, et al.
出版: (2012-01-01)