An accelerated PETALUTE MRI sequence for in vivo quantification of sodium content in human articular cartilage at 3T
Objective: In this work, we evaluate the sodium magnetic resonance imaging (MRI) capabilities of a three-dimensional (3D) dual-echo ultrashort echo time (UTE) sequence with a novel rosette petal trajectory (PETALUTE), in comparison to the 3D density-adapted (DA) radial spokes UTE sequence in human a...
| Main Authors: | , , , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
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Springer
2024
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| _version_ | 1826317236095156224 |
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| author | Villarreal, CX Shen, X Alhulail, AA Buffo, NM Zhou, X Pogue, E Özen, AC Chiew, M Sawiak, S Emir, U Chan, DD |
| author_facet | Villarreal, CX Shen, X Alhulail, AA Buffo, NM Zhou, X Pogue, E Özen, AC Chiew, M Sawiak, S Emir, U Chan, DD |
| author_sort | Villarreal, CX |
| collection | OXFORD |
| description | Objective: In this work, we evaluate the sodium magnetic resonance imaging (MRI) capabilities of a three-dimensional (3D) dual-echo ultrashort echo time (UTE) sequence with a novel rosette petal trajectory (PETALUTE), in comparison to the 3D density-adapted (DA) radial spokes UTE sequence in human articular cartilage in the knee. Materials and methods: We scanned five healthy subjects using a 3D dual-echo PETALUTE acquisition and two comparable implementations of 3D DA-radial spokes acquisitions, one matching the number of k-space projections (Radial – Matched Spokes) and the other matching the total number of samples (Radial – Matched Samples) acquired in k-space. Results: The PETALUTE acquisition enabled equivalent sodium quantification in articular cartilage volumes of interest (168.8 ± 29.9 mM, mean ± standard deviation) to those derived from the 3D radial acquisitions (171.62 ± 28.7 mM and 149.8 ± 22.2 mM, respectively). We achieved a 41% shorter scan time of 2:06 for 3D PETALUTE, compared to 3:36 for 3D radial acquisitions. We also evaluated the feasibility of further acceleration of the PETALUTE sequence through retrospective compressed sensing with 2 × and 4 × acceleration of the first echo and showed structural similarity of 0.89 ± 0.03 and 0.87 ± 0.03 when compared to non-retrospectively accelerated reconstruction. Conclusion: We demonstrate improved scan time with equivalent performance using a 3D dual-echo PETALUTE sequence compared to the 3D DA-radial sequence for sodium MRI of articular cartilage. |
| first_indexed | 2025-02-19T04:35:17Z |
| format | Journal article |
| id | oxford-uuid:bcd6c8ba-de67-4087-bf7c-0ad0cb90a66c |
| institution | University of Oxford |
| language | English |
| last_indexed | 2025-02-19T04:35:17Z |
| publishDate | 2024 |
| publisher | Springer |
| record_format | dspace |
| spelling | oxford-uuid:bcd6c8ba-de67-4087-bf7c-0ad0cb90a66c2025-01-27T20:07:24ZAn accelerated PETALUTE MRI sequence for in vivo quantification of sodium content in human articular cartilage at 3TJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:bcd6c8ba-de67-4087-bf7c-0ad0cb90a66cEnglishJisc Publications RouterSpringer2024Villarreal, CXShen, XAlhulail, AABuffo, NMZhou, XPogue, EÖzen, ACChiew, MSawiak, SEmir, UChan, DDObjective: In this work, we evaluate the sodium magnetic resonance imaging (MRI) capabilities of a three-dimensional (3D) dual-echo ultrashort echo time (UTE) sequence with a novel rosette petal trajectory (PETALUTE), in comparison to the 3D density-adapted (DA) radial spokes UTE sequence in human articular cartilage in the knee. Materials and methods: We scanned five healthy subjects using a 3D dual-echo PETALUTE acquisition and two comparable implementations of 3D DA-radial spokes acquisitions, one matching the number of k-space projections (Radial – Matched Spokes) and the other matching the total number of samples (Radial – Matched Samples) acquired in k-space. Results: The PETALUTE acquisition enabled equivalent sodium quantification in articular cartilage volumes of interest (168.8 ± 29.9 mM, mean ± standard deviation) to those derived from the 3D radial acquisitions (171.62 ± 28.7 mM and 149.8 ± 22.2 mM, respectively). We achieved a 41% shorter scan time of 2:06 for 3D PETALUTE, compared to 3:36 for 3D radial acquisitions. We also evaluated the feasibility of further acceleration of the PETALUTE sequence through retrospective compressed sensing with 2 × and 4 × acceleration of the first echo and showed structural similarity of 0.89 ± 0.03 and 0.87 ± 0.03 when compared to non-retrospectively accelerated reconstruction. Conclusion: We demonstrate improved scan time with equivalent performance using a 3D dual-echo PETALUTE sequence compared to the 3D DA-radial sequence for sodium MRI of articular cartilage. |
| spellingShingle | Villarreal, CX Shen, X Alhulail, AA Buffo, NM Zhou, X Pogue, E Özen, AC Chiew, M Sawiak, S Emir, U Chan, DD An accelerated PETALUTE MRI sequence for in vivo quantification of sodium content in human articular cartilage at 3T |
| title | An accelerated PETALUTE MRI sequence for in vivo quantification of sodium content in human articular cartilage at 3T |
| title_full | An accelerated PETALUTE MRI sequence for in vivo quantification of sodium content in human articular cartilage at 3T |
| title_fullStr | An accelerated PETALUTE MRI sequence for in vivo quantification of sodium content in human articular cartilage at 3T |
| title_full_unstemmed | An accelerated PETALUTE MRI sequence for in vivo quantification of sodium content in human articular cartilage at 3T |
| title_short | An accelerated PETALUTE MRI sequence for in vivo quantification of sodium content in human articular cartilage at 3T |
| title_sort | accelerated petalute mri sequence for in vivo quantification of sodium content in human articular cartilage at 3t |
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