Heterosexual transmission of human immunodeficiency virus type 1 variants associated with zidovudine resistance.
During zidovudine therapy, human immunodeficiency virus type 1 (HIV-1) acquires a distinctive set of mutations that diminish the sensitivity of the virus to this drug in vitro. An AIDS patient is described who, while being treated with zidovudine, transmitted HIV-1 bearing a drug resistance mutation...
Main Authors: | Conlon, C, Klenerman, P, Edwards, A, Larder, B, Phillips, R |
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Format: | Journal article |
Language: | English |
Published: |
1994
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