Generation of a novel mouse model for the inducible depletion of macrophages in vivo.

Macrophages play an essential role in tissue homeostasis, innate immunity, inflammation, and wound repair. Macrophages are also essential during development, severely limiting the use of mouse models in which these cells have been constitutively deleted. Consequently, we have developed a transgenic...

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Hlavní autoři: Gheryani, N, Coffelt, S, Gartland, A, Rumney, R, Kiss-Toth, E, Lewis, C, Tozer, G, Greaves, D, Dear, T, Miller, G
Médium: Journal article
Jazyk:English
Vydáno: 2013