Increasing plasma free fatty acids in healthy subjects induces aortic distensibility changes seen in obesity.

BACKGROUND: Elevated free fatty acid (FFA) levels are known to impair aortic elastic function. In obesity, FFA levels are elevated and aortic distensibility (AD) reduced in a pattern that predominantly affects the distal aorta. Despite this, the role of FFAs in obesity-related aortic stiffness remai...

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Bibliographic Details
Main Authors: Rider, O, Holloway, C, Emmanuel, Y, Bloch, E, Clarke, K, Neubauer, S
Format: Journal article
Language:English
Published: 2012