Effects of C-1-substituted glucose analogue on the activation states of glycogen synthase and glycogen phosphorylase in rat hepatocytes.

A series of glucose-analogue inhibitors of glycogen phosphorylase b (GPb) has been designed, synthesized and investigated in crystallographic binding and kinetic studies. The aim is to produce a compound that may exert more effective control over glycogen metabolism than the parent glucose molecule...

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Detalles Bibliográficos
Autores principales: Board, M, Bollen, M, Stalmans, W, Kim, Y, Fleet, G, Johnson, L
Formato: Journal article
Lenguaje:English
Publicado: 1995