Direct visualization of antigen-specific CD8+ T cells during the primary immune response to Epstein-Barr virus In vivo.

Primary infection with virus can stimulate a vigorous cytotoxic T cell response. The magnitude of the antigen-specific component versus the bystander component of a primary T cell response remains controversial. In this study, we have used tetrameric major histocompatibility complex-peptide complexe...

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Hlavní autoři: Callan, M, Tan, L, Annels, N, Ogg, G, Wilson, J, O'Callaghan, C, Steven, N, Mcmichael, A, Rickinson, AB
Médium: Journal article
Jazyk:English
Vydáno: 1998