Zn-ejection for the selective inhibition of JMJD2 histone demethylases

Zn-ejection for the selective inhibition of JMJD2 histone demethylases

Bibliographic Details
Main Authors:	Sekirnik, R, Rose, N, Mecinovic, J, Thalhammer, A, Schofield, C
Format:	Conference item
Published:	2012

Similar Items

Inhibition of the histone lysine demethylase JMJD2A by ejection of structural Zn(II).
by: Sekirnik, R, et al.
Published: (2009)

Inhibition of the histone demethylase JMJD2E by 3-substituted pyridine 2,4-dicarboxylates.
by: Thalhammer, A, et al.
Published: (2011)

Inhibition of the histone demethylase JMJD2E by 3-substituted pyridine 2,4-dicarboxylates.
by: Thalhammer, A, et al.
Published: (2011)

Selective inhibitors of the JMJD2 histone demethylases: combined nondenaturing mass spectrometric screening and crystallographic approaches.
by: Rose, N, et al.
Published: (2010)

Selective inhibitors of the JMJD2 histone demethylases: combined nondenaturing mass spectrometric screening and crystallographic approaches.
by: Rose, N, et al.
Published: (2010)

Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity.
by: Ng, S, et al.
Published: (2007)

The JMJD Family Histone Demethylases in Crosstalk Between Inflammation and Cancer
by: Jia Yang, et al.
Published: (2022-04-01)

Histone demethylase JmjD2A regulates neural crest specification.
by: Strobl-Mazzulla, P, et al.
Published: (2010)

Inhibitor scaffolds for 2-oxoglutarate-dependent histone lysine demethylases.
by: Rose, N, et al.
Published: (2008)

Inhibitor scaffolds for 2-oxoglutarate-dependent histone lysine demethylases.
by: Rose, N, et al.
Published: (2008)

Dioxygen binding in the active site of histone demethylase JMJD2A and the role of the protein environment
by: Cortopassi, W, et al.
Published: (2015)

Dioxygen binding in the active site of histone demethylase JMJD2A and the role of the protein environment
by: Cortopassi, W, et al.
Published: (2015)

Histone demethylases UTX and JMJD3 are required for NKT cell development in mice
by: Daniel Northrup, et al.
Published: (2017-05-01)

Histone Demethylase JMJD2D: A Novel Player in Colorectal and Hepatocellular Cancers
by: Qiang Chen, et al.
Published: (2022-06-01)

Regulation of adipogenesis by nucelar receptor PPARγ is modulated by the histone demethylase JMJD2C
by: Lizcano Fernando, et al.
Published: (2011-01-01)

Regulation of adipogenesis by nucelar receptor PPARγ is modulated by the histone demethylase JMJD2C
by: Lizcano Fernando, et al.
Published: (2011-01-01)

Histone Demethylase JMJD3 Mediated Doxorubicin-Induced Cardiomyopathy by Suppressing SESN2 Expression
by: Panxia Wang, et al.
Published: (2020-09-01)

2-Oxoglutarate oxygenases are inhibited by a range of transition metals.
by: Sekirnik, R, et al.
Published: (2010)

Inhibition of histone demethylases by 4-carboxy-2,2'-bipyridyl compounds.
by: Chang, K, et al.
Published: (2011)

The Histone Demethylase JMJD3 Regulates Smooth Muscle Differentiation and Is Associated With Blood Pressure
by: Kevin Mangum, et al.
Published: (2023-01-01)

The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
by: Chowdhury, R, et al.
Published: (2011)

The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases.
by: Chowdhury, R, et al.
Published: (2011)

The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
by: Chowdhury, R, et al.
Published: (2011)

The Functions of the Demethylase JMJD3 in Cancer
by: Anna Sanchez, et al.
Published: (2021-01-01)

SET7/9-mediated methylation affects oncogenic functions of histone demethylase JMJD2A
by: Ruicai Gu, et al.
Published: (2023-10-01)

The Histone Demethylase JMJD1C Regulates CAMKK2-AMPK Signaling to Participate in Cardiac Hypertrophy
by: Shuang Yu, et al.
Published: (2020-06-01)

The Histone Demethylase JMJD2A Modulates the Induction of Hypertrophy Markers in iPSC-Derived Cardiomyocytes
by: Wendy Rosales, et al.
Published: (2018-02-01)

The histone H3 lysine 27-specific demethylase Jmjd3 is required for neural commitment.
by: Thomas Burgold, et al.
Published: (2008-08-01)

Histone demethylase JMJD1C is phosphorylated by mTOR to activate de novo lipogenesis
by: Jose A. Viscarra, et al.
Published: (2020-02-01)

Enterotoxigenic Bacteroides fragilis induces the stemness in colorectal cancer via upregulating histone demethylase JMJD2B
by: Qian-Qian Liu, et al.
Published: (2020-11-01)

Highly selective inhibition of histone demethylases by de novo macrocyclic peptides
by: Kawamura, A, et al.
Published: (2017)

Targeting histone demethylases JMJD3 and UTX: selenium as a potential therapeutic agent for cervical cancer
by: Dezhi Chen, et al.
Published: (2024-04-01)

Histone demethylase JMJD6 regulates cellular migration and proliferation in adipose-derived mesenchymal stem cells
by: Chongyang Shen, et al.
Published: (2018-08-01)

Regulation of the JMJD3 (KDM6B) histone demethylase in glioblastoma stem cells by STAT3.
by: Maureen M Sherry-Lynes, et al.
Published: (2017-01-01)

SUMO modification of a heterochromatin histone demethylase JMJD2A enables viral gene transactivation and viral replication.
by: Wan-Shan Yang, et al.
Published: (2017-02-01)

Highly selective inhibition of histone demethylases by de novo macrocyclic peptides
by: Akane Kawamura, et al.
Published: (2017-04-01)

Control of enhancer and promoter activation in the type I interferon response by the histone demethylase Kdm4d/JMJD2d
by: Rohit Chandwani, et al.
Published: (2023-05-01)

Development of biochemical tools to characterise human H3K27 histone demethylase JmjD3
by: Che, KH
Published: (2013)

The histone demethylase JMJD2B is regulated by estrogen receptor alpha and hypoxia, and is a key mediator of estrogen induced growth.
by: Yang, J, et al.
Published: (2010)

Mechanisms of human histone and nucleic acid demethylases.
by: Walport, L, et al.
Published: (2012)