IL-33 promotes anemia during chronic inflammation by inhibiting differentiation of erythroid progenitors

An important comorbidity of chronic inflammation is anemia, which may be related to dysregulated activity of hematopoietic stem and progenitor cells (HSPCs) in the bone marrow (BM). Among HSPCs, we found that the receptor for IL-33, ST2, is expressed preferentially and highly on erythroid progenitor...

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Príomhchruthaitheoirí: Swann, JW, Koneva, LA, Regan-Komito, D, Sansom, SN, Powrie, F, Griseri, T
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: Rockefeller University Press 2020