Anti-Inflammatory Microglia/Macrophages as a Potential Therapeutic Target in Brain Metastasis

Anti-Inflammatory Microglia/Macrophages as a Potential Therapeutic Target in Brain Metastasis

Brain metastasis is a common complication of cancer patients and is associated with poor survival. Histological data from patients with brain metastases suggest that microglia are the major immune population activated around the metastatic foci. Microglia and macrophages have the ability to polarise...

Podrobná bibliografie
Hlavní autoři:	Andreou, K, Sarmiento Soto, M, Allen, D, Economopoulos, V, de Bernardi, A, Larkin, J, Sibson, N
Médium:	Journal article
Vydáno:	Frontiers Media 2017

Podobné jednotky

Anti-inflammatory Microglia/Macrophages As a Potential Therapeutic Target in Brain Metastasis
Autor: Kleopatra E. Andreou, a další
Vydáno: (2017-10-01)

Inhibition of Anti-Inflammatory Macrophage Phenotype Reduces Tumour Growth in Mouse Models of Brain Metastasis
Autor: Vasiliki Economopoulos, a další
Vydáno: (2022-03-01)

The multifarious role of microglia in brain metastasis
Autor: Sarmiento Soto, M, a další
Vydáno: (2018)

The Multifarious Role of Microglia in Brain Metastasis
Autor: Manuel Sarmiento Soto, a další
Vydáno: (2018-11-01)

Abstract 1561: Characterization of circulating monocyte infiltration in brain metastasis
Autor: Economopoulos, V, a další
Vydáno: (2016)

Mechanistic pathways underlying altered neurovascular coupling in brain metastasis
Autor: Sarmiento Soto, M, a další
Vydáno: (2016)

A brain metastasis therapy tweak, for the better? Concomitant stereotactic radiotherapy and molecular-targeted therapy
Autor: Soto, M, a další
Vydáno: (2017)

The ambiguity of brain metastasis response to radiotherapy driven by cellular adhesion molecules
Autor: Soto, M, a další
Vydáno: (2017)

Imaging of translocator protein upregulation is selective for pro‐inflammatory polarized astrocytes and microglia
Autor: Pannell, M, a další
Vydáno: (2019)

Characterising the role of microglia in the early stages of brain metastasis
Autor: Andreou, K
Vydáno: (2016)

STAT3-mediated astrocyte reactivity associated with brain metastasis contributes to neurovascular dysfunction
Autor: Sarmiento Soto, M, a další
Vydáno: (2020)

Editorial: The Role of the Immune Response in Brain Metastasis
Autor: Nicola R. Sibson, a další
Vydáno: (2022-05-01)

Targeting of adult microglia, the brain-resident macrophages
Autor: Wong, Ying Xin
Vydáno: (2016)

Mouse models of brain metastasis for unravelling tumour progression
Autor: Soto, MS, a další
Vydáno: (2016)

Optimization of molecularly targeted MRI in the brain: empirical comparison of sequences and particles
Autor: Zarghami, N, a další
Vydáno: (2018)

Optimization of molecularly targeted MRI in the brain: empirical comparison of sequences and particles
Autor: Zarghami N, a další
Vydáno: (2018-07-01)

Nrf2-mediated anti-inflammatory polarization of macrophages as therapeutic targets for osteoarthritis
Autor: Lin Wang, a další
Vydáno: (2022-08-01)

Microglia as target for anti-inflammatory approaches to prevent secondary brain injury after subarachnoid hemorrhage (SAH)
Autor: Rebecca Heinz, a další
Vydáno: (2021-01-01)

The roles of glioma-associated macrophages/microglia and potential targets for anti-glioma therapy
Autor: Hiroaki Matsuzaki, a další
Vydáno: (2024-10-01)

Disruption of tumour-host communication by downregulation of LFA-1 reduces COX-2 and e-NOS expression and inhibits brain metastasis growth
Autor: Sarmiento Soto, M, a další
Vydáno: (2016)

Mitochondrial Dysfunction, Macrophage, and Microglia in Brain Cancer
Autor: Rongze Olivia Lu, a další
Vydáno: (2021-01-01)

Targeted intracerebral delivery of the anti-inflammatory cytokine IL13 promotes alternative activation of both microglia and macrophages after stroke
Autor: Somayyeh Hamzei Taj, a další
Vydáno: (2018-06-01)

Editorial: Microglia as a Therapeutic Target for Brain Repair: Opportunities and Challenges
Autor: Kai Zhou, a další
Vydáno: (2022-03-01)

The Flavonoid Agathisflavone Directs Brain Microglia/Macrophages to a Neuroprotective Anti-Inflammatory and Antioxidant State via Regulation of NLRP3 Inflammasome
Autor: Balbino Lino dos Santos, a další
Vydáno: (2023-05-01)

A novel molecular magnetic resonance imaging agent targeting activated leukocyte cell adhesion molecule as demonstrated in mouse brain metastasis models
Autor: Zarghami, N, a další
Vydáno: (2020)

Functional role of endothelial adhesion molecules in the early stages of brain metastasis.
Autor: Soto, MS, a další
Vydáno: (2014)

Administration route governs the therapeutic efficacy, biodistribution and macrophage targeting of anti-inflammatory nanoparticles in the lung
Autor: Lu Wang, a další
Vydáno: (2021-02-01)

Effect of Erdene urel on Microglia / Macrophage Distribution and Inhibition of Inflammatory Response after Brain Ischemia in Rats
Autor: Hu Yu Rong, a další
Vydáno: (2020-04-01)

Development of an early brain metastasis geometric model for Geant4-DNA simulation
Autor: Falzone, N, a další
Vydáno: (2016)

Long-term characterization of activated microglia/macrophages facilitating the development of experimental brain metastasis through intravital microscopic imaging
Autor: Sha Qiao, a další
Vydáno: (2019-01-01)

Brain-derived neurotrophic factor (BDNF) has direct anti-inflammatory effects on microglia
Autor: Tryston Charlton, a další
Vydáno: (2023-06-01)

Role of the systemic immune system in brain metastasis.
Autor: Hamilton, A, a další
Vydáno: (2013)

Role of the systemic immune system in brain metastasis
Autor: Hamilton, A, a další
Vydáno: (2012)

Dosimetric evaluation of radionuclides for VCAM-1-targeted radionuclide therapy in an early brain metastasis model
Autor: Falzone, N, a další
Vydáno: (2018)

Conditional knockout of ASK1 in microglia/macrophages attenuates epileptic seizures and long-term neurobehavioural comorbidities by modulating the inflammatory responses of microglia/macrophages
Autor: Yiying Zhang, a další
Vydáno: (2022-08-01)

Immune Microenvironment of Brain Metastases—Are Microglia and Other Brain Macrophages Little Helpers?
Autor: Hua You, a další
Vydáno: (2019-08-01)

The Contribution of Macrophage Plasticity to Inflammatory Arthritis and Their Potential as Therapeutic Targets
Autor: Karina Kulakova, a další
Vydáno: (2024-09-01)

Innate Immune Cells: Monocytes, Monocyte-Derived Macrophages and Microglia as Therapeutic Targets for Alzheimer’s Disease and Multiple Sclerosis
Autor: Adham Fani Maleki, a další
Vydáno: (2019-07-01)

Anti-inflammatory effects of glaucocalyxin B in microglia cells
Autor: Ping Gan, a další
Vydáno: (2015-05-01)

Neopterin In Immunological Reactions In Cancer and In the Brain Possible Involvement of Macrophages and Microglia
Autor: Sawada Makuto
Vydáno: (1995-11-01)