Kinetic isotope effects on the dissolution kinetics of solid salicylic acid in aqueous solution: Evidence for solubilisation via a proton dissociation-recombination mechanism
Quantitative Atomic Force Microscopy measurements made on the dissolving surface of solid salicylic acid in H2O and D2O reveal a kinetic isotope effect (kH/kD = 2.3 ± 0.6) on the dissolution rate consistent with a transition state in which the proton is dissociated from the dissolving molecule.
| Main Authors: | , , |
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| Formato: | Journal article |
| Idioma: | English |
| Publicado em: |
2002
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