Acute disseminated encephalomyelitis and its place amongst other acute inflammatory demyelinating CNS disorders.

The diagnosis of acute inflammatory demyelinating CNS conditions is complex and this is reflected in variations in how cohorts are defined across studies. For some conditions the diagnosis relies on whether it is monophasic or relapsing, in others the anatomical site of inflammation is used as a mea...

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Main Author: Palace, J
Format: Journal article
Language:English
Published: 2011
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author Palace, J
author_facet Palace, J
author_sort Palace, J
collection OXFORD
description The diagnosis of acute inflammatory demyelinating CNS conditions is complex and this is reflected in variations in how cohorts are defined across studies. For some conditions the diagnosis relies on whether it is monophasic or relapsing, in others the anatomical site of inflammation is used as a means of categorisation. Clinical features such as precipitants, gender and age may affect the probability of certain diagnoses, but are not highly accurate. Exclusive features for the pathology are identifiable for some but not all conditions, and are seldom available during life. Specific markers such as antibodies are informative and new developments in this area are likely in the near future. This review outlines the features and classification of acute disseminated encephalomyelitis and contrasts it with other related conditions before attempting to define a pragmatic organisation of these conditions based upon present evidence.
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spelling oxford-uuid:bd9398ec-ac30-40be-887d-58bf31b854f22022-03-27T05:32:51ZAcute disseminated encephalomyelitis and its place amongst other acute inflammatory demyelinating CNS disorders.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:bd9398ec-ac30-40be-887d-58bf31b854f2EnglishSymplectic Elements at Oxford2011Palace, JThe diagnosis of acute inflammatory demyelinating CNS conditions is complex and this is reflected in variations in how cohorts are defined across studies. For some conditions the diagnosis relies on whether it is monophasic or relapsing, in others the anatomical site of inflammation is used as a means of categorisation. Clinical features such as precipitants, gender and age may affect the probability of certain diagnoses, but are not highly accurate. Exclusive features for the pathology are identifiable for some but not all conditions, and are seldom available during life. Specific markers such as antibodies are informative and new developments in this area are likely in the near future. This review outlines the features and classification of acute disseminated encephalomyelitis and contrasts it with other related conditions before attempting to define a pragmatic organisation of these conditions based upon present evidence.
spellingShingle Palace, J
Acute disseminated encephalomyelitis and its place amongst other acute inflammatory demyelinating CNS disorders.
title Acute disseminated encephalomyelitis and its place amongst other acute inflammatory demyelinating CNS disorders.
title_full Acute disseminated encephalomyelitis and its place amongst other acute inflammatory demyelinating CNS disorders.
title_fullStr Acute disseminated encephalomyelitis and its place amongst other acute inflammatory demyelinating CNS disorders.
title_full_unstemmed Acute disseminated encephalomyelitis and its place amongst other acute inflammatory demyelinating CNS disorders.
title_short Acute disseminated encephalomyelitis and its place amongst other acute inflammatory demyelinating CNS disorders.
title_sort acute disseminated encephalomyelitis and its place amongst other acute inflammatory demyelinating cns disorders
work_keys_str_mv AT palacej acutedisseminatedencephalomyelitisanditsplaceamongstotheracuteinflammatorydemyelinatingcnsdisorders